A part of MilliporeSigma

07-794 | Anti-Rab13 Antibody

100 µg  
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      Replacement Information

      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, M, R WB, IP, IF Rb Affinity Purified Polyclonal Antibody
      Catalogue Number07-794
      Brand Family Upstate
      Trade Name
      • Upstate
      DescriptionAnti-Rab13 Antibody
      Background InformationRab proteins are members of the Ras superfamily of small G-Proteins. At least 60 isoforms have been identified. These GTPases are primarily involved in vesicle trafficking and it is believed that a different Rab protein may be needed for each step of the vesicular transport. It is thought Rab4 and Rab11 are involved in internalization, sorting, and transport to lysosomes or recycling, of several membrane proteins, including GPCRs, GLUT-4, Aquaporin-2, or the H+/K+ ATPase.
      Product Information
      FormatAffinity Purified
      • PC12 Cell Lysate
      PresentationAffinity Purified rabbit IgG in storage buffer containing tri-citrate-phosphate, pH 7-8 and 0.1% sodium azide.
      ApplicationDetect Rab13 using this Anti-Rab13 Antibody validated for use in WB, IP & IF.
      Key Applications
      • Western Blotting
      • Immunoprecipitation
      • Immunofluorescence
      Application NotesImmunofluorescence Staining:
      Independent laboratory demonstrated this antibody worked in Immunofluorescence studies at a 1:100-1:500 dilution.

      Immunoprecipitation (IP):
      Independent laboratory demonstrated this antibody works in Immunoprecipitation.
      Biological Information
      ImmunogenSythnetic peptide of amno acids 129-148 of rat Rab13
      SpecificityRecognizes Rab13
      Species Reactivity
      • Human
      • Mouse
      • Rat
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • Rab13
      • RAB13, member RAS oncogene family
      • GIG4
      • growth-inhibiting gene 4 protein
      UniProt Number
      UniProt SummaryFUNCTION: Could participate in polarized transport, in the assembly and/or the activity of tight junctions.
      SIZE: 203 amino acids; 22,774 Da
      SUBCELLULAR LOCATION:Cell junction › tight junction. Cell membrane; Lipid-anchor; Cytoplasmic side. Cytoplasmic vesicle membrane; Lipid-anchor; Cytoplasmic side. Note= Cytoplasmic tight junctions or associated with vesicles scattered throughout the cytoplasm in cells lacking tight junctions.
      TISSUE SPECIFICITY: Detected in several types of epithelia, including intestine, kidney, liver and in endothelial cells.
      SIMILARITY: Belongs to the small GTPase superfamily. Rab family.
      Molecular Weight25 kDa
      Physicochemical Information
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceWestern Blot Analysis:
      This lot detected Rab13 at 1:1,000 (1g/mL) dilution in lysates from PC12 lysate resolved via SDS-PAGE and transferred to PVDF (Immobilon-P).
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Handling Recommendations: Upon receipt, and prior to removing the cap, centrifuge the vial and gently mix the solution. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information


      Certificates of Analysis

      TitleLot Number
      Anti-Rab13 - 2066037 2066037
      Anti-Rab13 - 2153565 2153565
      Anti-Rab13 - 2239831 2239831
      Anti-Rab13 - 2289141 2289141
      Anti-Rab13 - NG1527857 NG1527857
      Anti-Rab13 -2817235 2817235


      Reference overviewPub Med ID
      Involvement of Rab13 and JRAB/MICAL-L2 in epithelial cell scattering.
      Kanda, I, et al.
      Oncogene, 27: 1687-95 (2008) 2008

      17891173 17891173
      In vivo and in vitro characterization of novel neuronal plasticity factors identified following spinal cord injury.
      Di Giovanni, Simone, et al.
      J. Biol. Chem., 280: 2084-91 (2005) 2005

      15522871 15522871
      Rab13 mediates the continuous endocytic recycling of occludin to the cell surface.
      Morimoto, Shinya, et al.
      J. Biol. Chem., 280: 2220-8 (2005) 2005

      Show Abstract
      15528189 15528189
      Rab13 regulates PKA signaling during tight junction assembly.
      Köhler, Katja, et al.
      J. Cell Biol., 165: 175-80 (2004) 2004

      Show Abstract
      15096524 15096524