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MABE614 | Anti-RPS3, clone EPR7808, Rabbit Monoclonal Antibody

100 µL  
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      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, R, M WB, IHC Rb Unpurified Monoclonal Antibody
      Catalogue NumberMABE614
      DescriptionAnti-RPS3, clone EPR7808, Rabbit Monoclonal Antibody
      Alternate Names
      • 40S ribosomal protein S3
      • RPS3
      • OK/SW-cl.26
      Background Information40S ribosomal protein S3, and encoded by the gene name RPS3 or OK/SW-cl.26, is a ribosomal protein that is a component of the 40S subunit, where it forms part of the domain where translation is initiated. This protein belongs to the S3P family of ribosomal proteins. Studies of the mouse and rat proteins have demonstrated that the protein has an extraribosomal role as an endonuclease involved in the repair of UV-induced DNA damage. RPS3 appears to be located in both the cytoplasm and nucleus but not in the nucleolus. Higher levels of expression of this protein in colon adenocarcinomas and adenomatous polyps compared to adjacent normal colonic mucosa have been observed.
      Product Information
      PresentationRabbit monoclonal in buffer containing PBS with up to 0.1% sodium azide, 0.05% BSA, and 50% glycerol.
      ApplicationThis Anti-RPS3 antibody is validated for use in WB, IH for the detection of RPS3.
      Key Applications
      • Western Blotting
      • Immunohistochemistry
      Application NotesImmunohistochemistry Analysis: A 1:50-100 dilution from a representative lot detected RPS3 in human kidney tissue.

      Produced in collaboration with Epitomics™
      Biological Information
      ImmunogenSynthetic peptide corresponding to human RPS3.
      ConcentrationPlease refer to lot specific datasheet.
      SpecificityEquilibrium disassociation constant (KD) is 1.36 x 10 -10 M
      Species Reactivity
      • Human
      • Rat
      • Mouse
      Antibody TypeMonoclonal Antibody
      Gene Symbol
      • RPS3
      • OK/SW-cl.26
      Purification MethodUnpurified
      UniProt Number
      Molecular Weight~30 kDa observed. Uncharacterized bands may be observed in some lysate(s).
      Physicochemical Information
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in HepG2, PC-12, and Neuro-2a cell lysates.

      Western Blotting Analysis: A 1:1,000-10,000 dilution of this antibody detected RPS3 in HepG2, PC-12, and Neuro-2a cell lysates.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at -20°C from date of receipt.
      Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
      Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.
      Packaging Information
      Material Size100 µL
      Transport Information
      Supplemental Information

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      Life Science Research > Antibodies and Assays > Primary Antibodies