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MAB5652 | Anti-Prox1 Antibody, clone 5G10

MAB5652
100 µg  
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      Overview

      Replacement Information

      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      Ch, H, M, R, Lz WB, IHC M Purified Monoclonal Antibody
      Description
      Catalogue NumberMAB5652
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionAnti-Prox1 Antibody, clone 5G10
      Alternate Names
      • Homeobox prospero-like protein PROX1
      References
      Product Information
      FormatPurified
      PresentationLiquid in PBS with 0.1% sodium azide.
      Applications
      ApplicationThis Anti-Prox1 Antibody, clone 5G10 is validated for use in WB, IH for the detection of Prox1.
      Key Applications
      • Western Blotting
      • Immunohistochemistry
      Application NotesWestern Blot: 2 μg/mL
      This antibody is recommended for immunohistochemistry use.

      Optimal working dilutions must be determined by end user.
      Biological Information
      ImmunogenRecombinant human Prox1 protein.
      Clone5G10
      HostMouse
      SpecificityProx1. By Western blot the antibody recognizes a ~83 kDa protein in fetal mouse brain lysate.
      IsotypeIgG
      Species Reactivity
      • Chicken
      • Human
      • Mouse
      • Rat
      • Lizard
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • PROX1
      Purification MethodProtein A Purfied
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: Q92786 # May play a fundamental role in early development of CNS. May regulate gene expression and development of postmitotic undifferentiated young neurons (By similarity).
      SIZE: 737 amino acids; 83203 Da
      SUBCELLULAR LOCATION: Nucleus (Probable).
      TISSUE SPECIFICITY: Most actively expressed in the developing lens. Detected also in embryonic brain, lung, liver and kidney. In adult, it is more abundant in heart and liver than in brain, skeletal muscle, kidney and pancreas.
      SIMILARITY: SwissProt: Q92786 ## Belongs to the Prospero homeobox family. & Contains 1 Prospero-type homeobox DNA-binding domain.
      Molecular Weight83 kDa
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain at 2-8degC in undiluted aliquots for up to 6 months after date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      SDS

      Title

      Safety Data Sheet (SDS) 

      Certificates of Analysis

      TitleLot Number
      MOUSE ANTI-PROX1 MONOCLONAL ANTIBODY - 2121761 2121761
      MOUSE ANTI-PROX1 MONOCLONAL ANTIBODY - 2379342 2379342
      MOUSE ANTI-PROX1 MONOCLONAL ANTIBODY - 2455699 2455699
      MOUSE ANTI-PROX1 MONOCLONAL ANTIBODY - 2109515 2109515
      MOUSE ANTI-PROX1 MONOCLONAL ANTIBODY - 2210341 2210341
      MOUSE ANTI-PROX1 MONOCLONAL ANTIBODY - 2274009 2274009
      MOUSE ANTI-PROX1 MONOCLONAL ANTIBODY - 2295668 2295668

      References

      Reference overviewApplicationPub Med ID
      The role of egr1 in early zebrafish retinogenesis.
      Zhang, L; Cho, J; Ptak, D; Leung, YF
      PloS one 8 e56108 2013

      Show Abstract
      Immunohistochemistry23405257 23405257
      Monocyte chemoattractant protein-1 affects migration of hippocampal neural progenitors following status epilepticus in rats.
      Hung, YW; Lai, MT; Tseng, YJ; Chou, CC; Lin, YY
      Journal of neuroinflammation 10 11 2013

      Show Abstract
      Immunohistochemistry23339567 23339567
      A Bmp reporter with ultrasensitive characteristics reveals that high Bmp signaling is not required for cortical hem fate.
      Doan, LT; Javier, AL; Furr, NM; Nguyen, KL; Cho, KW; Monuki, ES
      PloS one 7 e44009 2012

      Show Abstract
      22984456 22984456
      The tumor suppressor gene Trp53 protects the mouse lens against posterior subcapsular cataracts and the BMP receptor Acvr1 acts as a tumor suppressor in the lens.
      Wiley, LA; Rajagopal, R; Dattilo, LK; Beebe, DC
      Disease models & mechanisms 4 484-95 2011

      Show Abstract
      21504908 21504908
      Activation of ERK by spontaneous seizures in neural progenitors of the dentate gyrus in a mouse model of epilepsy.
      Yi Li,Zechun Peng,Bo Xiao,Carolyn R Houser
      Experimental neurology 224 2010

      Show Abstract Full Text Article
      20226181 20226181
      Integrin alpha4beta1 signaling is required for lymphangiogenesis and tumor metastasis.
      Garmy-Susini B, Avraamides CJ, Schmid MC, Foubert P, Ellies LG, Barnes L, Feral C, Papayannopoulou T, Lowy A, Blair SL, Cheresh D, Ginsberg M, Varner JA
      Cancer Res 70 3042-51. Epub 2010 Apr 13. 2010

      Show Abstract Full Text Article
      20388801 20388801
      The tumor suppressor merlin is required for cell cycle exit, terminal differentiation, and cell polarity in the developing murine lens.
      Luke A Wiley,Lisa K Dattilo,Kai B Kang,Marco Giovannini,David C Beebe
      Investigative ophthalmology & visual science 51 2010

      Show Abstract Full Text Article
      20181838 20181838
      Production of monoclonal antibodies against Prox1.
      Chen, Xiaoren, et al.
      Hybridoma (Larchmt), 25: 27-33 (2006) 2006

      Show Abstract
      16475879 16475879

      Data Sheet

      Title
      Anti-PROX1, clone 5G10 - Data Sheet

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      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies