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MAB5654 | Anti-Prox1 Antibody, clone 4G10

MAB5654
100 µg  
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      Overview

      Replacement Information

      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      Ch, H, M, R, Lz WB, IHC M Purified Monoclonal Antibody
      Description
      Catalogue NumberMAB5654
      ReplacesMABE488
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionAnti-Prox1 Antibody, clone 4G10
      Alternate Names
      • Homeobox prospero-like protein PROX1
      References
      Product Information
      FormatPurified
      PresentationLiquid in PBS with 0.1% sodium azide.
      Applications
      ApplicationAnti-Prox1 Antibody, clone 4G10 is an antibody against Prox1 for use in WB, IH.
      Key Applications
      • Western Blotting
      • Immunohistochemistry
      Application NotesWestern blot: 2 μg/mL

      Optimal working dilutions must be determined by end user.
      Biological Information
      ImmunogenRecombinant human Prox1 protein.
      Cloneclone 4G10
      HostMouse
      SpecificityProx1. By Western blot the antibody recognizes a ~83 kDa protein in fetal mouse brain lysate.
      IsotypeIgG
      Species Reactivity
      • Chicken
      • Human
      • Mouse
      • Rat
      • Lizard
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • PROX1
      Purification MethodProtein A Purfied
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: Q92786 # May play a fundamental role in early development of CNS. May regulate gene expression and development of postmitotic undifferentiated young neurons (By similarity).
      SIZE: 737 amino acids; 83203 Da
      SUBCELLULAR LOCATION: Nucleus (Probable).
      TISSUE SPECIFICITY: Most actively expressed in the developing lens. Detected also in embryonic brain, lung, liver and kidney. In adult, it is more abundant in heart and liver than in brain, skeletal muscle, kidney and pancreas.
      SIMILARITY: SwissProt: Q92786 ## Belongs to the Prospero homeobox family. & Contains 1 Prospero-type homeobox DNA-binding domain.
      Molecular Weight83 kDa
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain at 2-8degC in undiluted aliquots for up to 6 months after date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      SDS

      Title

      Safety Data Sheet (SDS) 

      Certificates of Analysis

      TitleLot Number
      MOUSE ANTI-PROX1 MONOCLONAL ANTIBODY - 2142172 2142172
      MOUSE ANTI-PROX1 MONOCLONAL ANTIBODY - 2430540 2430540
      MOUSE ANTI-PROX1 MONOCLONAL ANTIBODY - 2037181 2037181
      MOUSE ANTI-PROX1 MONOCLONAL ANTIBODY - 2106890 2106890
      MOUSE ANTI-PROX1 MONOCLONAL ANTIBODY - 2109516 2109516
      MOUSE ANTI-PROX1 MONOCLONAL ANTIBODY - 2297249 2297249
      MOUSE ANTI-PROX1 MONOCLONAL ANTIBODY -2489033 2489033
      MOUSE ANTI-PROX1 MONOCLONAL ANTIBODY -2571572 2571572
      MOUSE ANTI-PROX1 MONOCLONAL ANTIBODY -2649191 2649191
      MOUSE ANTI-PROX1 MONOCLONAL ANTIBODY -2683902 2683902
      MOUSE ANTI-PROX1 MONOCLONAL ANTIBODY -2697595 2697595
      MOUSE ANTI-PROX1 MONOCLONAL ANTIBODY -2710753 2710753
      MOUSE ANTI-PROX1 MONOCLONAL ANTIBODY -2823590 2823590

      References

      Reference overviewApplicationPub Med ID
      Onecut1 is essential for horizontal cell genesis and retinal integrity.
      Wu, F; Li, R; Umino, Y; Kaczynski, TJ; Sapkota, D; Li, S; Xiang, M; Fliesler, SJ; Sherry, DM; Gannon, M; Solessio, E; Mu, X
      The Journal of neuroscience : the official journal of the Society for Neuroscience 33 13053-65, 13065a 2013

      Show Abstract
      23926259 23926259
      Cerebral organoids model human brain development and microcephaly.
      Lancaster, MA; Renner, M; Martin, CA; Wenzel, D; Bicknell, LS; Hurles, ME; Homfray, T; Penninger, JM; Jackson, AP; Knoblich, JA
      Nature 501 373-9 2013

      Show Abstract
      Immunohistochemistry23995685 23995685
      The Spalt family transcription factor Sall3 regulates the development of cone photoreceptors and retinal horizontal interneurons.
      de Melo, J; Peng, GH; Chen, S; Blackshaw, S
      Development (Cambridge, England) 138 2325-36 2011

      Show Abstract Full Text Article
      21558380 21558380
      Prox1 regulates the notch1-mediated inhibition of neurogenesis.
      Kaltezioti, V; Kouroupi, G; Oikonomaki, M; Mantouvalou, E; Stergiopoulos, A; Charonis, A; Rohrer, H; Matsas, R; Politis, PK
      PLoS biology 8 e1000565 2010

      Show Abstract
      21203589 21203589
      Production of monoclonal antibodies against Prox1.
      Chen, Xiaoren, et al.
      Hybridoma (Larchmt), 25: 27-33 (2006) 2006

      Show Abstract
      16475879 16475879

      Data Sheet

      Title
      MOUSE ANTI-PROX1

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      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies