A part of MilliporeSigma

MABC645 | Anti-PSP94 Antibody, clone EPR7345, rabbit monoclonal

100 µL  
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      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H WB, IHC Rb Unpurified Monoclonal Antibody
      Catalogue NumberMABC645
      DescriptionAnti-PSP94 Antibody, clone EPR7345, rabbit monoclonal
      Alternate Names
      • Beta-microseminoprotein
      • Immunoglobulin-binding factor
      • IGBF
      • PN44
      • Prostate secreted seminal plasma protein
      • Prostate secretory protein of 94 amino acids
      • PSP-94
      • PSP94
      • Seminal plasma beta-inhibin
      Background InformationBeta-microseminoprotein, prostate secreted seminal plasma protein, and prostate secretory protein of 94 amino acids (PSP94) are all names for a secreted protein originally found in the seminal fluid and on the surface of sperm. In fact, PSP94 along with PSA (Prostate-specific Antigen) and PAP (Prostate Acid Phosphatase) are the three most abundant proteins in seminal fluid. PSP94 is expressed in prostate, liver, kidney, breast and penis. PSP94 is additionally expressed in pancreas, esophagus, stomach, duodenum, colon, trachea, lung, salivary glands and fallopian tube but to a lower level. As with other prostate-secreted proteins, PSP94 can get into the blood particularly during prostate epithelial tumor formation, and thus PSP94 levels can be an indicator of possible tumor growth. Moreover the differential change in PSP94 expression between hormone-dependent, less aggressive prostate cancers, where PSP94 is high to hormone-independent prostate cancers where PSP94 expression is low or non-existent potentially makes PSP94 a marker that can be used to distinguish between these two types of prostate cancer forms. EMD-Millipore’s Anti-PSP94 rabbit monoclonal antibody has been tested in western blot on human prostate tissue and human prostate cancer cell line lysates and in immunohistochemistry on paraffin embedded human prostate tissue sections.
      Product Information
      • Human prostate and prostate cancer tissue lysates
      PresentationRabbit monoclonal in buffer containing PBS with up to 0.1% sodium azide, 0.05% BSA, and 50% glycerol.
      ApplicationDetect prostate secreted seminal plasma protein using this rabbit monoclonal antibody, Anti-PSP94 Antibody, clone EPR7345 validated for use in western blotting & IHC.
      Key Applications
      • Western Blotting
      • Immunohistochemistry
      Application NotesImmunohistochemistry Analysis: A 1:500-1,000 dilution from a representative lot detected PSP94 in human prostate tissue.

      Optimal working dilutions must be determined by end user.
      Biological Information
      ImmunogenSynthetic peptide corresponding to human PSP94.
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Gene Symbol
      • MSMB
      • PRSP
      Purification MethodUnpurified
      UniProt Number
      Molecular Weight~16 kDa observed.
      Physicochemical Information
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in human prostate and prostate cancer tissue lysates.

      Western Blotting Analysis: A 1:10,000-50,000 dilution of this antibody detected PSP94 in human prostate and prostate cancer tissue lysates.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at -20°C from date of receipt.
      Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
      Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.
      Packaging Information
      Material Size100 µL
      Transport Information
      Supplemental Information