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AB3341 | Anti-PRMT3 NT Antibody

AB3341
100 µg  
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      Overview

      Replacement Information

      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H ELISA, WB Rb Purified Polyclonal Antibody
      Description
      Catalogue NumberAB3341
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionAnti-PRMT3 NT Antibody
      References
      Product Information
      FormatPurified
      PresentationPurified immunoglobulin. Liquid in PBS containing 0.09% sodium azide.
      Applications
      ApplicationDetect PRMT3 N-terminal with Anti-PRMT3 N-terminal Antibody (Rabbit Polyclonal Antibody), that has been shown to work in ELISA & WB.
      Key Applications
      • ELISA
      • Western Blotting
      Application NotesWestern Blot: 1:100-1:500. Reacts with a band of approximately 57 kDa on whole HL60 cell lysate. Additional bands may be present depending on sample used.

      ELISA (direct): 1:1,000

      Optimal working dilutions must be determined by the end user.
      Biological Information
      ImmunogenSynthetic peptide from N-terminus of human PRMT3.
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostRabbit
      SpecificityReacts with PRMT3 (Protein Arginine N-Methytransferase 3).
      Species Reactivity
      • Human
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Entrez Gene SummaryType I protein arginine N-methyltransferases (PRMTs), such as PRMT3, catalyze the formation of asymmetric N(G),N(G)-dimethylarginine (ADMA) residues in proteins (Tang et al., 1998 [PubMed 9642256]).[supplied by OMIM]
      Gene Symbol
      • PRMT3
      • HRMT1L3
      • EC 2.1.1.-
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: O60678 # Methylates (mono and asymmetric dimethylation) the guanidino nitrogens of arginyl residues in some proteins.
      SIZE: 531 amino acids; 59903 Da
      SUBUNIT: May exist as a monomer or homodimer (By similarity).
      SUBCELLULAR LOCATION: Cytoplasm.
      DOMAIN: SwissProt: O60678 The zinc-finger is responsible for substrate specificity (By similarity).
      SIMILARITY: Belongs to the protein arginine N-methyltransferase family. & Contains 1 C2H2-type zinc finger.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      SDS

      Title

      Safety Data Sheet (SDS) 

      Certificates of Analysis

      TitleLot Number
      RABBIT ANTI-PRMT3 N-TERMINAL POLYCLONAL ANTIBODY - 2436294 2436294
      RABBIT ANTI-PRMT3 -2622672 2622672

      References

      Reference overviewPub Med ID
      Exposure on cell surface and extensive arginine methylation of ewing sarcoma (EWS) protein.
      Belyanskaya, L L, et al.
      J. Biol. Chem., 276: 18681-7 (2001) 2001

      11278906 11278906
      Genomic organization, physical mapping, and expression analysis of the human protein arginine methyltransferase 1 gene.
      Scorilas, A, et al.
      Biochem. Biophys. Res. Commun., 278: 349-59 (2000) 2000

      Show Abstract
      11097842 11097842
      PRMT3 is a distinct member of the protein arginine N-methyltransferase family. Conferral of substrate specificity by a zinc-finger domain.
      Frankel, A and Clarke, S
      J. Biol. Chem., 275: 32974-82 (2000) 2000

      Show Abstract
      10931850 10931850

      Data Sheet

      Title
      Anti-PRMT3 N-terminal - Data Sheet