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ABS1106 | Anti-PPM1L Antibody

100 µL  
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      Replacement Information

      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H WB, IHC, ICC Rb Affinity Purified Polyclonal Antibody
      Catalogue NumberABS1106
      DescriptionAnti-PPM1L Antibody
      Alternate Names
      • Protein phosphatase 1L
      • Protein phosphatase 1-like
      • Protein phosphatase 2C isoform epsilon
      • PP2C-epsilon
      • PPM1L
      Background InformationProtein phosphatase 1L, also known as, Protein phosphatase 1-like or Protein phosphatase 2C isoform epsilon (PP2C-epsilon), and encoded by the gene name(s), PPM1L or PP2CE, acts as a suppressor of the SAPK signaling pathways by associating with and dephosphorylating MAP3K7/TAK1 and MAP3K5. PPM1L is localized to the membrane and is ubiquitously expressed with high levels found in heart, placenta, lung, liver, kidney and pancreas.
      Product Information
      FormatAffinity Purified
      PresentationPurified rabbit polyclonal in buffer containing PBS (pH 7.2) with 0.02% sodium azide and 40% glycerol.
      ApplicationThis Anti-PPM1L Antibody is validated for use in Western Blotting, Immunohistochemistry and Immunocytochemistry for the detection of PPM1L.
      Key Applications
      • Western Blotting
      • Immunohistochemistry
      • Immunocytochemistry
      Application NotesImmunohistochemistry Analysis: A 1:20-50 dilution from a representative lot detected PPM1L in skeletal muscle and heart tissues.

      Immunocytochemistry Analysis: 1-4 μg/mL from a representative lot detected PPM1L in A431 cells.

      Biological Information
      ImmunogenRecombinant protein corresponding to human PPM1L.
      ConcentrationPlease refer to lot specific datasheet.
      Species Reactivity
      • Human
      Antibody TypePolyclonal Antibody
      Gene Symbol
      • PPM1L
      • PP2CE
      Purification MethodAffinity
      UniProt Number
      Molecular Weight~42 kDa observed. Uncharacterized bands may be observed in some lysate(s).
      Physicochemical Information
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in Negative control (vector only transfected HEK293T) and over-expression (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T) cell lysates.

      Western Blotting Analysis: A 1:100-250 dilution of this antibody detected PPM1L in over-expression (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T) cell lysates.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at -20°C from date of receipt.
      Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
      Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.
      Packaging Information
      Material Size100 µL
      Transport Information
      Supplemental Information