A part of MilliporeSigma

07-095 | Anti-PP2A-methylesterase/PME-1 Antibody

200 µg  
Retrieving price...
Price could not be retrieved
Minimum Quantity needs to be mulitiple of
Upon Order Completion More Information
You Saved ()
Request Pricing
Limited AvailabilityLimited Availability
Limited Quantities Available
    Remaining : Will advise
      Remaining : Will advise
      Will advise
      Contact Customer Service

      Special Offers


      Contact Customer Service

      Click To Print This Page


      Replacement Information

      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, M, R WB Rb Purified Polyclonal Antibody
      Catalogue Number07-095
      Brand Family Upstate
      Trade Name
      • Upstate
      DescriptionAnti-PP2A-methylesterase/PME-1 Antibody
      Product Information
      Presentation0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30%
      ApplicationThis Anti-PP2A-methylesterase/PME-1 Antibody is validated for use in IP, WB for the detection of PP2A-methylesterase/PME-1.
      Key Applications
      • Western Blotting
      Biological Information
      ImmunogenA mixture of two nickel agarose-purified, His6-tagged, bacterial expressed human Protein Phosphatase Methylesterase-1 (PME-1) fragments (residues 225-302 and 277-387). These two fragments represent the carboxyl-terminal portion of the protein.
      SpecificityProtein Phosphatase Methylesterase-1
      Species Reactivity
      • Human
      • Mouse
      • Rat
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Entrez Gene SummaryProtein phosphatase methylesterase-1 catalyzes the demethylation of the protein phosphatase-2A catalytic subunit (PPP2CA; MIM 176915) (Ogris et al., 1999 [PubMed 10318862]).[supplied by OMIM]
      Gene Symbol
      • PPME1
      • FLJ22226
      • PME-1
      Purification MethodProtein A chromatography
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: Q9Y570 # Demethylates proteins that have been reversibly carboxymethylated. Demethylates PPP2CB (in vitro).
      SIZE: 386 amino acids; 42315 Da
      SUBUNIT: Binds PPP2CB.
      SIMILARITY: SwissProt: Q9Y570 ## Belongs to the AB hydrolase superfamily.
      Molecular Weight44kDa
      Physicochemical Information
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality Assuranceroutinely evaluated by immunoblot on RIPA lysates from mouse 3T3 fibroblasts
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage Conditions2 years at -20°C
      Packaging Information
      Material Size200 µg
      Transport Information
      Supplemental Information




      Safety Data Sheet (SDS) 

      Certificates of Analysis

      TitleLot Number
      Anti-PP2A-methylesterase/PME-1 - 20083 20083
      Anti-Protein Phosphatase Methylesterase-1 (rabbit polyclonal IgG) - 2127185 2127185
      Anti-Protein Phosphatase Methylesterase-1 (rabbit polyclonal IgG) - 2183667 2183667
      Anti-Protein Phosphatase Methylesterase-1 (rabbit polyclonal IgG) - 2273963 2273963
      Anti-Protein Phosphatase Methylesterase-1 (rabbit polyclonal IgG) - JBC1931635 JBC1931635
      Anti-Protein Phosphatase Methylesterase-1 -2633738 2633738
      Anti-Protein Phosphatase Methylesterase-1 -2763851 2763851
      Anti-Protein Phosphatase Methylesterase-1 -2805155 2805155


      Reference overviewApplicationPub Med ID
      Single-pot enzymatic synthesis of Dicer-substrate siRNAs.
      Guiley, KZ; Pratt, AJ; MacRae, IJ
      Nucleic acids research 40 e40 2012

      Show Abstract
      Western Blotting22189103 22189103
      A protein phosphatase methylesterase (PME-1) is one of several novel proteins stably associating with two inactive mutants of protein phosphatase 2A.
      Ogris, E, et al.
      J. Biol. Chem., 274: 14382-91 (1999) 1999

      Show Abstract
      10318862 10318862

      Related Products & Applications

      Included Positive Control

      Catalog Number Description  
      12-305 3T3/A31 Cell Lysate Show Pricing & Availability

      Related Products By: Brand Facete


      Life Science Research > Antibodies and Assays > Primary Antibodies