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07-2186 | Anti-PI3K Type 3 Antibody

100 µg  
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      Replacement Information

      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, M ICC Rb Affinity Purified Polyclonal Antibody
      Catalogue Number07-2186
      DescriptionAnti-PI3K Type 3 Antibody
      Alternate Names
      • Phosphatidylinositol 3-kinase catalytic subunit type 3
      • PI3-kinase type 3
      • PI3K type 3
      • PtdIns-3-kinase type 3
      • Phosphatidylinositol 3-kinase p100 subunit
      • Phosphoinositide-3-kinase class 3
      • hVps34
      Background InformationPI3K Type 3, also known as Phosphatidylinositol 3-kinase catalytic subunit type 3, Phosphatidylinositol 3-kinase p100 subunit, Phosphoinositide-3-kinase class 3, hVps34, PI3-kinase type 3, PI3K type 3, or PtdIns-3-kinase type 3, and encoded by the gene PIK3C3/VPS34, is the catalytic subunit of the PI3K complex that mediates the formation of phosphatidylinositol 3-phosphate which plays a key role in initiation and maturation of autophagosomes and the initiation of autophagy. PI3K Type 3 is also involved in the transport of lysosomal enzyme precursors to lysosomes. Additionally, PI3K Type 3 is required for cytokinesis. PI3K Type 3 is localized to the cytoplasm and endosomes. PI3K Type 3 is expressed in most cells and is particularly high in skeletal muscle.
      Product Information
      FormatAffinity Purified
      PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      ApplicationDetect PI3K Type 3 using this Anti-PI3K Type 3 Antibody validated for use in ICC.
      Key Applications
      • Immunocytochemistry
      Biological Information
      ImmunogenKLH-conjugated linear peptide corresponding to the C-terminus of human PI3K Type 3.
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      Species Reactivity
      • Human
      • Mouse
      Species Reactivity NoteHuman and Mouse. Predicted to react with Rat, Canine, Feline, Horse, Cow, Primate, Porcine, and Camelid based on 100% sequence homology.
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • PIK3C3
      • VPS34
      Purification MethodAffinity Purfied
      UniProt Number
      Molecular Weight101 kDa calculated
      Physicochemical Information
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Immunocytochemistry Analysis in HeLa cells.

      Immunocytochemistry Analysis: A 1:100 dilution of this antibody detected PI3K Type 3 in HeLa cells.

      Dylight® is a registered trademark of Thermo Fisher Scientific.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information

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      Life Science Research > Antibodies and Assays > Primary Antibodies