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AB3503-I | Anti-PDX-1 Antibody

AB3503-I
100 µL  
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      Overview

      Replacement Information

      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, M WB, IHC Rb Affinity Purified Polyclonal Antibody
      Description
      Catalogue NumberAB3503-I
      DescriptionAnti-PDX-1 Antibody
      Alternate Names
      • Pancreas/duodenum homeobox protein 1
      • PDX-1
      • Glucose-sensitive factor
      • GSF
      • Insulin promoter factor 1
      • IPF-1
      • Insulin upstream factor 1
      • IUF-1
      • Islet/duodenum homeobox-1
      • IDX-1
      • Somatostatin-transactivating factor 1
      • STF-1
      Background InformationPancreatic and duodenal homeobox 1, also known as PDX1, and Insulin promoter factor 1 is a human gene. This islet-specific protein activates transcription of the insulin andsomatostatin genes. It is a key regulator of islet peptide hormone expressionn and also plays an essential role in pancreatic development. Mutations in this gene may be involved in several disorders of the pancreas or in diabetes mellitus.
      References
      Product Information
      FormatAffinity Purified
      PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Applications
      ApplicationThis Anti-PDX-1 Antibody is validated for use in Western Blotting and Immunohistochemistry for the detection of PDX-1.
      Key Applications
      • Western Blotting
      • Immunohistochemistry
      Application NotesImmunohistochemistry Analysis: A 1:50 dilution from a representative lot detected pdx-1 in the islets of Langerhans of human and mouse pancreas.
      Biological Information
      ImmunogenKLH-conjugated linear peptide corresponding to region amino acids 90-120 of human PDX-1.
      ConcentrationPlease refer to lot specific datasheet.
      HostRabbit
      SpecificityRecognizes PDX-1
      Species Reactivity
      • Human
      • Mouse
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • PDX1
      • IPF1
      • STF1
      Purification MethodAntigen Affinity Purified
      UniProt Number
      Molecular Weight~38 kDa observed
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in mouse pancreatic beta cell tissue lysate.

      Western Blotting Analysis: A 1:4,000 dilution of this antibody detected PDX-1 in mouse pancreatic beta cell tissue lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µL
      Transport Information
      Supplemental Information
      Specifications

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      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies