A part of MilliporeSigma

MABC281 | Anti-OTUD7B Antibody, clone 90-46-126

100 µg  
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      Replacement Information

      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H WB M Purified Monoclonal Antibody
      Catalogue NumberMABC281
      DescriptionAnti-OTUD7B Antibody, clone 90-46-126
      Alternate Names
      • OTU domain-containing protein 7B
      • Cellular zinc finger anti-NF-kappa-B protein
      • Zinc finger A20 domain-containing protein 1
      • Zinc finger protein Cezanne
      Background InformationOTU domain-containing protein 7B (OTUD7B) is also called Cellular zinc finger anti-NF-kappa-B protein, Zinc finger A20 domain-containing protein 1 and Zinc finger protein Cezanne. OTUD7B negatively regulates the NF-kappa-B pathway and mucosal immunity against infections, as well as mediates EGFR deubiquitination. OTUD7B shows deubiquitinating activity for 'Lys-11', 'Lys-48' or 'Lys-63'-linked polyubiquitin chains. OTUD7B is widely expressed, but is especially abundant in kidney, heart and fetal liver. OTUD7B is also differentially expressed in B-cells during distinct developmental stages, with higher expression levels found in primary immature B-cells as compared to mature cells.
      Product Information
      • Hep2 cell lysate
      PresentationPurified mouse monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      ApplicationAnti-OTUD7B Antibody, clone 90-46-126 is a highly specific mouse monoclonal antibody & that targets OTU domain-containing protein 7B & has been tested in western blotting.
      Key Applications
      • Western Blotting
      Application NotesWestern Blotting Analysis: 0.5 µg/mL from a representative lot detected OTUD7B in 10 µg of MCF-7 cell lysate.

      Biological Information
      ImmunogenHis-tagged recombinant protein corresponding to human OTUD7B.
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • OTUD7B
      • ZA20D1
      Purification MethodProtein G Purified
      UniProt Number
      Molecular Weight93 kDa calculated. Uniprot states known isoform at ~89 kDa.
      Physicochemical Information
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in Hep2 cell lysate.

      Western Blotting Analysis: 0.5 µg/mL of this antibody detected OTUD7B in 10 µg of Hep2 cell lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information