A part of MilliporeSigma

MAB5220 | Anti-NMDAR2B Antibody, clone 13A11

100 µg  
Retrieving price...
Price could not be retrieved
Minimum Quantity needs to be mulitiple of
Upon Order Completion More Information
You Saved ()
Request Pricing
Limited AvailabilityLimited Availability
Limited Quantities Available
    Remaining : Will advise
      Remaining : Will advise
      Will advise
      Contact Customer Service

      Special Offers


      Contact Customer Service

      Click To Print This Page


      Replacement Information

      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H ICC, IHC, WB M Purified Monoclonal Antibody
      Catalogue NumberMAB5220
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionAnti-NMDAR2B Antibody, clone 13A11
      Alternate Names
      • NR2B
      Product Information
      PresentationAffinity purified immunoglobulin. Liquid in PBS. Contains no preservative.
      ApplicationAnti-NMDAR2B Antibody, clone 13A11 is an antibody against NMDAR2B for use in IC, IH & WB.
      Key Applications
      • Immunocytochemistry
      • Immunohistochemistry
      • Western Blotting
      Application NotesImmunohistochemistry (light and EM) on 4% paraformaldehyde & 0.125% glutaraldehyde fixed tissue: 2.5-5 μg/mL.

      Immunocytochemistry: 2.5-5.0 μg/mL

      Western blot: 1-5 μg/mL Optimal working dilutions must be determined by end user.
      Biological Information
      ImmunogenAmino acid region 1033-1161 from human NMDAR2B produced as a GST fusion protein.
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Entrez Gene SummaryN-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA receptor channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of three different subunits: NR1 (GRIN1), NR2 (GRIN2A, GRIN2B, GRIN2C, or GRIN2D) and NR3 (GRIN3A or GRIN3B). The NR2 subunit acts as the agonist binding site for glutamate. This receptor is the predominant excitatory neurotransmitter receptor in the mammalian brain.
      Gene Symbol
      • GRIN2B
      • MGC142180
      • Glutamate
      • NMDAR2B
      • NR3
      • NR2B
      • MGC142178
      • hNR3
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: Q13224 # NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine.
      SIZE: 1484 amino acids; 166367 Da
      SUBUNIT: Forms heteromeric channel of a zeta subunit (GRIN1), a epsilon subunit (GRIN2A, GRIN2B, GRIN2C or GRIN2D) and a third subunit (GRIN3A or GRIN3B). Found in a complex with GRIN1 and GRIN3B. Found in a complex with GRIN1, GRIN3A and PPP2CB. Interacts with PDZ domains of INADL and DLG4 (By similarity).
      SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
      TISSUE SPECIFICITY: Primarily found in the fronto-parieto-temporal cortex and hippocampus pyramidal cells, lower expression in the basal ganglia.
      SIMILARITY: SwissProt: Q13224 ## Belongs to the glutamate-gated ion channel (TC 1.A.10) family.
      Physicochemical Information
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain frozen at -20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information




      Safety Data Sheet (SDS) 

      Certificates of Analysis

      TitleLot Number
      MOUSE ANTI-NMDAR2B -2632531 2632531
      MOUSE ANTI-NMDAR2B -2695263 2695263
      MOUSE ANTI-NMDAR2B -2788830 2788830


      Reference overviewPub Med ID
      The N-methyl-D-aspartate receptor type 2A is frequently methylated in human colorectal carcinoma and suppresses cell growth.
      Kim, MS; Chang, X; Nagpal, JK; Yamashita, K; Baek, JH; Dasgupta, S; Wu, G; Osada, M; Woo, JH; Westra, WH; Trink, B; Ratovitski, EA; Moon, C; Sidransky, D
      Oncogene 27 2045-54 2008

      Show Abstract
      17922030 17922030


      Pathways and Biomarkers of Glutamatergic Synapse Flyer (EMD)

      Data Sheet

      Anti-NMDAR2B, clone 13A11 - Data Sheet

      Related Products & Applications

      Related Products

      Catalog Number Description  
      04-1148 Anti-phospho-NMDAR2B (Ser1303) Antibody, clone EP1858Y, rabbit monoclonal Show Pricing & Availability
      05-920 Anti-NR2B Antibody, clone BWJHL Show Pricing & Availability
      06-600 Anti-NR2B Antibody Show Pricing & Availability
      07-398 Anti-phospho-NR2B (Ser1303) Antibody Show Pricing & Availability
      AB15362 Anti-NMDAR2B Antibody Show Pricing & Availability
      AB1557 Anti-NMDAR2B Antibody, pain Show Pricing & Availability
      AB1557P Anti-NMDAR2B Antibody Show Pricing & Availability
      AB5403 Anti-NMDAR2B Antibody, phosphoTyr 1472 Show Pricing & Availability
      AB9630 Anti-NMDAR2B phospho Tyr1252 Antibody Show Pricing & Availability
      AB9690 Anti-NMDAR2B phospho Tyrosine 1336 Antibody Show Pricing & Availability
      FCABS332F Milli-Mark™ Anti-NR2B-FITC Antibody Show Pricing & Availability
      MAB5574 Anti-NMDAR2B Antibody Show Pricing & Availability
      MAB5778 Anti-NMDAR2B Antibody, CT Show Pricing & Availability
      MAB5780 Anti-NMDAR2B Antibody Show Pricing & Availability
      MAB5782 Anti-NMDAR2B Antibody, NT Show Pricing & Availability

      Alternative Packsize

      Catalog Number Description  
      MAB5220-KC Anti-NMDAR2B, clone 13A11 (KC) Show Pricing & Availability

      View Gene Related Products for this Target


      Life Science Research > Antibodies and Assays > Primary Antibodies