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AB1094 | Anti-Myosin X Antibody

100 µL  
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      Replacement Information

      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, M, R WB Rb Serum Polyclonal Antibody
      Catalogue NumberAB1094
      DescriptionAnti-Myosin X Antibody
      Alternate Names
      • Unconventionnal myosin-X
      • Unconventional myosin-10
      Background InformationMyosins are a superfamily of molecular motor proteins found in eukaryotic cells. Motor proteins are involved in muscular contraction, cytokinesis, short-range membrane/vesicle transport and a host of other cellular processes. The myosins are responsible for actin-based motility by using the energy of ATP hydrolysis to generate force and movement along actin filaments. There are many isoforms of myosin of which some have specialized functions in certain cell types (such as muscle), while other isoforms are ubiquitous. Myosin X belongs to a group of myosin isoforms known as unconventional myosins that participate in cellular processes ranging from membrane trafficking to signaling and cell motility. Myosin X is concentrated at the tips of filopodia and Myosin X rich regions travel forward and backward along filopods, (Berg, 2002). It also appears that Myosin X functions in actual filopodia formation, (Bohil, 2006).
      Product Information
      • Human head/neck lysate.
      PresentationRabbit serum containing 0.05% NaN3.
      ApplicationDetect Myosin X using this Anti-Myosin X Antibody validated for use in WB.
      Key Applications
      • Western Blotting
      Biological Information
      ImmunogenKLH-conjugated synthetic peptide to amino acids 936-953 of human Myosin X.
      Epitopea.a. 936-953
      SpecificityCat. No. AB1094 recognizes human Myosin X.
      Species Reactivity
      • Human
      • Mouse
      • Rat
      Species Reactivity NoteHuman. Predicted to cross react with mouse and rat based on 100% sequence homology. Reactivity with other species has not been tested.
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • MYO10
      UniProt Number
      UniProt SummaryFUNCTION: Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments. Plays a role in regions of dynamic actin.

      SUBUNIT STRUCTURE: Interacts with ECM29.

      CAUTION: Represents a unconventional myosin. This protein should not be confused with the conventional myosin-10 (MYH10).

      SIZE: 237 kDa
      Molecular Weight~ 108 kDa
      Physicochemical Information
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated on a representative lot by Western blot on human head/neck lysate using Anti-Myosin X.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain at -20°C for up to 1 year from date of receipt.
      Upon arrival, aliquot into usable quantities to avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
      Packaging Information
      Material Size100 µL
      Transport Information
      Supplemental Information