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05-683 | Anti-Mps1 Antibody, CT, clone 4-112-3

200 µg  
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      Replacement Information

      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H IP, WB, ICC M Purified Monoclonal Antibody
      Catalogue Number05-683
      Brand Family Upstate
      Trade Name
      • Upstate
      DescriptionAnti-Mps1 Antibody, CT, clone 4-112-3
      OverviewThis antibody is known to inhibit the autophos-phorylation/kinase activity of Mps1; Mps1 was previously known as TTK/PYK
      Product Information
      Presentation0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30%
      ApplicationAnti-Mps1 Antibody, CT, clone 4-112-3 is a high quality Mouse Monoclonal Antibody for the detection of Mps1 & has been validated in IP, WB, ICC.
      Key Applications
      • Immunoprecipitation
      • Western Blotting
      • Immunocytochemistry
      Biological Information
      ImmunogenHis-tagged fusion protein corresponding to amino acids 3-856 of human Mps1
      Cloneclone 4-112-3
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • TTK
      • PYT
      • MPS1L1
      • ESK
      • FLJ38280
      Purification MethodProtein G Chromatography
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P33981 # Phosphorylates proteins on serine, threonine, and tyrosine. Probably associated with cell proliferation.
      SIZE: 857 amino acids; 97072 Da
      TISSUE SPECIFICITY: Present in rapidly proliferating cell lines.
      SIMILARITY: SwissProt: P33981 ## Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. & Contains 1 protein kinase domain.
      Molecular Weight97kDa
      Physicochemical Information
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality Assuranceroutinely evaluated by immunoblot on HeLa total cell extract
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage Conditions2 years at -20°C
      Packaging Information
      Material Size200 µg
      Transport Information
      Supplemental Information




      Safety Data Sheet (SDS) 

      Certificates of Analysis

      TitleLot Number
      Anti-Mps1, CT, clone 4-112-3 (mouse monoclonal IgG1) - 2250526 2250526
      Anti-Mps1, CT, clone 4-112-3 (mouse monoclonal IgG1) - 2361826 2361826
      Anti-Mps1, CT, clone 4-112-3 - 22462 22462
      Anti-Mps1, CT, clone 4-112-3 - DAM1564471 DAM1564471
      Anti-Mps1, CT, clone 4-112-3 - DAM1731736 DAM1731736
      Anti-Mps1, CT, clone 4-112-3 - JBC1938932 JBC1938932
      Anti-Mps1, CT, clone 4-112-3 -2609845 2609845


      Reference overviewPub Med ID
      Human Mps1 kinase is required for the spindle assembly checkpoint but not for centrosome duplication.
      Stucke, Volker M, et al.
      EMBO J., 21: 1723-32 (2002) 2002

      11927556 11927556

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      Life Science Research > Antibodies and Assays > Primary Antibodies