A part of MilliporeSigma

AB2258 | Anti-Melanin Concentrating Hormone Antibody

100 µg   
Retrieving price...
Price could not be retrieved
Minimum Quantity needs to be mulitiple of
Upon Order Completion More Information
You Saved ()
Request Pricing
Limited AvailabilityLimited Availability
Limited Quantities Available
    Remaining : Will advise
      Remaining : Will advise
      Will advise
      Contact Customer Service

      Special Offers


      Contact Customer Service

      Click To Print This Page


      Replacement Information

      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, M, R WB, IHC, IH(P) Rb Serum Polyclonal Antibody
      Catalogue NumberAB2258
      DescriptionAnti-Melanin Concentrating Hormone Antibody
      Alternate Names
      • pro-melanin-concentrating hormone
      Background InformationMelanin is associated with pigment; however, melanin concentrating hormone project widely throughout the brain and function to regulate feeding behavior and energy balance. Mammalian MCH is present in neurons of both the central and peripheral nervous systems, with predominant expression in the lateral hypothalamus and zona incerta. Although MCH has been implicated in a variety of physiological functions, its central role in the control of feeding and energy balance has been the focus of previous studies. When administered centrally, MCH promotes food intake. It’s expression in the lateral hypothalamus is induced by starvation. Diseases associated with melanin are Albinoism and Parkinson's disease.
      Product Information
      • Mouse brain lysate.
      PresentationRabbit polyclonal serum in buffer containing 0.1M Tris-Glycine (pH7.4) 150mM NaCl with 0.05% NaN3.
      ApplicationAnti-Melanin Concentrating Hormone Antibody is an antibody against Melanin Concentrating Hormone for use in WB, IH, IH(P).
      Key Applications
      • Western Blotting
      • Immunohistochemistry
      • Immunohistochemistry (Paraffin)
      Application NotesImmunohistochemistry: 1:50 -1:500 dilution of this lot detected melanin using IHC-Select Detection with HRP-DAB.
      Biological Information
      ImmunogenKLH conjugated followed by melanin.
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      SpecificityCat. # AB2258 recognizes melanin concentrating hormone.
      Species Reactivity
      • Human
      • Mouse
      • Rat
      Species Reactivity NoteHuman Rat and Mouse. Predicted to react with rat, oppossum, chimpanzee, pig, cow and dog.
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • MCH
      Purification MethodProtein A Purfied
      UniProt Number
      UniProt SummaryTissue specificity: Expressed in testis and brain. Ref.3 Ref.4
      Developmental stage: Expressed in developing brain, found in fetal newborn and adult brain. Ref.4
      Sequence similarities: Belongs to the melanin-concentrating hormone family.
      Caution: Ref.3 reported that PMCHL1 mRNA may not be used as template for translation as only antisense PMCHL1 transcripts are present in brain

      Molecular WeightApprox. 19 kDa
      Physicochemical Information
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceRoutinely evaluated by Western Blot on mouse brain lysates.

      Western Blot Analysis:
      1:1,000 -1:10,000 dilution of this lot detected melanin on 10 µg of mouse brain lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8ºC from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information