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MABN668 | Anti-Ly6C Antibody, clone 6C3

MABN668
100 µL  
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      Overview

      Replacement Information

      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      M FC, DB R Purified Monoclonal Antibody
      Description
      Catalogue NumberMABN668
      DescriptionAnti-Ly6C Antibody, clone 6C3
      Alternate Names
      • Lymphocyte antigen 6C2
      • Ly-6C2
      Background InformationLymphocyte antigen 6C2 (Ly6C) is a 131 AA long membrane protein that is linked to macrophage phenotype according to expression levels.
      References
      Product Information
      FormatPurified
      PresentationPurified rat monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Applications
      ApplicationDetect Lymphocyte antigen 6C2 using this rat monoclonal antibody, Anti-Ly6C Antibody, clone 6C3 validated for use in Flow Cytometry & Dot Blot.
      Key Applications
      • Flow Cytometry
      • Dot Blot
      Application NotesDot Blot Analysis: A representative lot from an independent laboratory detected Ly6C in bone marrow-derived monocytes expressing 6C3 (Butovsky, O., et al. (2012). J Clin Invest. 122(9):3063-3087.).
      Biological Information
      ImmunogenWhole cells expressing mouse Ly6C.
      Clone6C3
      HostRat
      IsotypeIgG2aκ
      Species Reactivity
      • Mouse
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • Ly6c2
      • Ly6c
      Purification MethodProtein G Purified
      UniProt Number
      Molecular Weight14 kDa calculated
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Flow Cytometry in mouse spleen cells.

      Flow Cytometry Analysis: 1 µg of this antibody detected Ly6C in 1X10E6 mouse spleen cells.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µL
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      SDS

      Title

      Safety Data Sheet (SDS) 

      Certificates of Analysis

      TitleLot Number
      Anti-Ly6C, clone 6C3 - Q2273117 Q2273117
      Anti-Ly6C, clone 6C3 -2753827 2753827

      References

      Reference overviewPub Med ID
      Modulating inflammatory monocytes with a unique microRNA gene signature ameliorates murine ALS.
      Butovsky, O; Siddiqui, S; Gabriely, G; Lanser, AJ; Dake, B; Murugaiyan, G; Doykan, CE; Wu, PM; Gali, RR; Iyer, LK; Lawson, R; Berry, J; Krichevsky, AM; Cudkowicz, ME; Weiner, HL
      The Journal of clinical investigation 122 3063-87 2012

      Show Abstract
      22863620 22863620