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AB10557 | Anti-Lhx2 Antibody

100 µg  
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      Replacement Information

      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H IHC Rb Affinity Purified Polyclonal Antibody
      Catalogue NumberAB10557
      DescriptionAnti-Lhx2 Antibody
      Alternate Names
      • Homeobox protein LH-2
      • LIM HOX gene 2
      • LIM homeobox 2
      • LIM homeobox protein 2
      Background InformationLIM homeobox 2, also known as LHX2, is a gene that belongs to the LIM homeobox family. These genes seem to play an important role in asymmetric cell division, tissue specification and differentiation of specific cell types. LHX2 is expressed in developing B-cells, the forebrain, liver, during embryonic development when limbs and organs are developing, in the optic stalk, and olfactory epithelia. Studies have shown that under-expression of LHX2 during embryonic development causes hepatic fibrosis.
      Product Information
      FormatAffinity Purified
      • Human hippocampal and mouse cerebellum tissue.
      PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH7.4) 150 mM NaCl with 0.05% sodium azide.
      ApplicationThis Anti-Lhx2 Antibody is validated for use in IH for the detection of Lhx2.
      Key Applications
      • Immunohistochemistry
      Biological Information
      ImmunogenThis antibody is generated from rabbits immunized with a KLH conjugated linear peptide selected from residues of human LHX2.
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      SpecificityThis antibody recognizes LHX2.
      Species Reactivity
      • Human
      Species Reactivity NoteDemonstrated to react with human. Expected to react with horse, dog, and cow (93%) homology. Mouse (80%) homology.
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • LH-2
      • LH2
      • MGC138390
      • OTTHUMP00000022092
      • hLhx2
      Purification MethodAffinity Purfied
      UniProt Number
      UniProt SummaryFUNCTION: Transcriptional regulatory protein involved in the control of cell differentiation in developing lymphoid and neural cell types By similarity.
      SUBCELLULAR LOCATION: Nucleus Probable.
      SEQUENCE SIMILARITIES: Contains 1 homeobox DNA-binding domain.
      Contains 2 LIM zinc-binding domains.
      Molecular WeightApprox. 44 kDa
      Physicochemical Information
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Immunohistochemistry in human hippocampal and mouse cerebellum tissue.
      Immunohistochemistry Analysis: 1:100-500 dilution of this lot detected LHX2 in human hippocampal tissue and mouse cerebellum.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain refrigerated at 2-8°C for up to 12 months.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information




      Safety Data Sheet (SDS) 

      Certificates of Analysis

      TitleLot Number
      Anti-LHX2 - 2459520 2459520
      Anti-LHX2 - 1959699 1959699
      Anti-LHX2 - 2276385 2276385
      Anti-LHX2 - 2309159 2309159
      Anti-LHX2 - NRG1635486 NRG1635486
      Anti-LHX2 -2517766 2517766
      Anti-LHX2 -2691277 2691277
      Anti-LHX2 -2697504 2697504


      Reference overviewPub Med ID
      Development of retinal pigment epithelium from human parthenogenetic embryonic stem cells and microRNA signature.
      Li, WB; Zhang, YS; Lu, ZY; Dong, LJ; Wang, FE; Dong, R; Li, XR
      Investigative ophthalmology & visual science 53 5334-43 2012

      Show Abstract
      22736612 22736612

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      Life Science Research > Antibodies and Assays > Primary Antibodies