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ABE723 | Anti-LRWD1 Antibody

100 µL  
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      Replacement Information

      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H IHC, ICC Rb Affinity Purified Polyclonal Antibody
      Catalogue NumberABE723
      DescriptionAnti-LRWD1 Antibody
      Alternate Names
      • Leucine-rich repeat and WD repeat-containing protein 1
      • ORC-associated protein
      • ORCA
      • Origin recognition complex-associated protein
      • LRWD1
      Background InformationLeucine-rich repeat and WD repeat-containing protein 1, also known as, ORC-associated protein or ORCA or Origin recognition complex-associated protein, and encoded by the gene name(s), LRWD1 or ORCA, is associated component of the origin recognition complex (orc required to recruit and stabilize the orc complex to chromatin). Probably required for the association of orc on chromatin during g1 to establish pre-replication complex (prerc and to heterochromatic sites in post-replicated cells). Binds a combination of dna and histone methylation repressive marks on heterochromatin: binds histone h3 and h4 trimethylation marks h3k9me3;h3k27me3 and h4k20me3 in a cooperative manner with dna methylation. It is unclear whether it recognizes and binds these repressive marks by itself or needs additional factors.
      Product Information
      FormatAffinity Purified
      PresentationPurified rabbit polyclonal in buffer containing PBS (pH 7.2) with 0.02% sodium azide and 40% glycerol.
      ApplicationAnti-LRWD1 Antibody is an antibody against LRWD1 for use in Immunohistochemistry, Immunocytochemistry.
      Key Applications
      • Immunohistochemistry
      • Immunocytochemistry
      Application NotesImmunocytochemistry Analysis (ICC): 1-4 μg/mL from a representative lot detected LRWD1 in human A431 cells.

      Biological Information
      ImmunogenRecombinant protein corresponding to human LRWD1.
      ConcentrationPlease refer to lot specific datasheet.
      Species Reactivity
      • Human
      Antibody TypePolyclonal Antibody
      Gene Symbol
      • LRWD1
      • ORCA
      Purification MethodAffinity
      UniProt Number
      Molecular Weight71 kDa calculated
      Physicochemical Information
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceImmunohistochemistry Analysis (IHC): A 1:50-200 dilution from a representative lot detected LRWD1 in human testis tissue.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at -20°C from date of receipt.
      Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
      Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.
      Packaging Information
      Material Size100 µL
      Transport Information
      Supplemental Information