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ABN175 | Anti-LRRTM1 Antibody

ABN175
100 µg  
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      Overview

      Replacement Information

      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H WB Rb Affinity Purified Polyclonal Antibody
      Description
      Catalogue NumberABN175
      DescriptionAnti-LRRTM1 Antibody
      Alternate Names
      • Leucine-rich repeat transmembrane neuronal protein 1
      Background InformationLeucine-rich repeat transmembrane neuronal protein 1 (LRRTM1) is a multidomain postsynaptic protein. It contains nine leucine-rich repeats, one LRRCT domain, and 1 LRRNT domain. The Leucine-rich repeat transmembrane neuronal proteins bind to presynaptic neurexins and promote cell adhesion. The Leucine-rich repeat transmembrane neuronal protein 1 is predominantly expressed in the forebrain and may play a role in differentiation and connectivity processes during the development of this region. The corresponding gene is imprinted in humans, and has been linked to neurodevelopmental disorders, such as schizophrenia. Mice deficient in LRRTM1 show cognitive deficits in various behavioral paradigms.
      References
      Product Information
      FormatAffinity Purified
      Control
      • Human salivary gland tissue lysate
      PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Applications
      ApplicationDetect the LRRTM1 protein using this Anti-LRRTM1 validated for use in WB.
      Key Applications
      • Western Blotting
      Application NotesWestern Blot Analysis: 2 µg/mL from a representative lot detected LRRTM1 in 10 µg of human fetal brain tissue lysate.
      Biological Information
      ImmunogenKLH-conjugated linear peptide corresponding to the cytoplasmic domain of human LRRTM1.
      EpitopeCytoplasmic domain
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostRabbit
      SpecificityThis antibody recognizes the cytoplasmic domain of LRRTM1.
      Species Reactivity
      • Human
      Species Reactivity NoteDemonstrated to react with Human. Predicted to react with Mouse, Rat, Bovine, Canine, and Rhesus Macaque based on 100% sequence homology.
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • LRRTM1
      Purification MethodAffinity Purfied
      UniProt Number
      Molecular Weight~59 kDa observed. An uncharacterized band may appear at ~18 kDa in some lysates.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blot in human salivary gland tissue lysate.

      Western Blot Analysis: 2 µg/mL of this antibody detected LRRTM1 in 10 µg of human salivary gland tissue lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications

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      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies