438192 Anti-LRP, Light Chain Mouse mAb (5A6)

438192
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      Overview

      Replacement Information

      Key Specifications Table

      Species ReactivityHostAntibody Type
      H, M, Rb M Monoclonal Antibody

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      438192-100UG
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      Stocked 
      Discontinued
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          Plastic ampoule 100 μg
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          Description
          OverviewRecognizes the ~85 kDa LRP protein.
          Catalogue Number438192
          Brand Family Calbiochem®
          SynonymsAnti-Low Density Lipoprotein Receptor-Related Protein
          Application Data
          Detection of light chain LRP by immunoblotting. Samples: Soluble LRP at 500 ng (lane 1) and 50 ng (lane 2) with prestained standard (lane 3). Primary antibody: Anti-LRP, Light Chain Mouse mAb (5A6) (Cat. No. 438192) (1 µg/ml). Detection: chemiluminescence.
          References
          ReferencesMikhailenko, I., et al. 2001. J. Biol. Chem. 276, 39484.
          Rebeck, W.G., et al. 2001. Mol. Brain Res. 87, 238.
          Coukos, G., et al. 1994. Am. J. Pathol. 144, 383.
          Daugherty, A., and Rateri, D.L. 1994. Arterioscler Thromb. 14, 2017.
          Strickland, D.K., et al. 1990. J. Biol. Chem. 265, 17401.
          Product Information
          FormLiquid
          FormulationIn 100 mM NaCl, 50 mM sodium phosphate, 1 mM EDTA, pH 6.6.
          PreservativeNone
          Applications
          Application ReferencesParaffin Sections Coukos, G., et al. 1994. Am. J. Pathol. 144, 383. Daugherty, A., and Rateri, D.L. 1994. Arterioscler Thromb. 14, 2017. Rebeck, G.W., et al. 1993. Neuron 11, 575.
          Key Applications Frozen Sections
          Immunoblotting (Western Blotting)
          Paraffin Sections
          Application NotesFrozen Sections (1-5 µg/ml)
          Immunoblotting (1-5 µg/ml)
          Paraffin Sections (1-5 µg/ml, see application references)
          Application CommentsVariables associated with assay conditions will dictate the proper working dilution.
          Biological Information
          Immunogenpurified, human placenta LRP
          ImmunogenHuman
          Clone5A6
          HostMouse
          IsotypeIgG₂
          Species Reactivity
          • Human
          • Mouse
          • Rabbit
          Antibody TypeMonoclonal Antibody
          Concentration Label Please refer to vial label for lot-specific concentration
          Physicochemical Information
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Dry Ice Only
          Toxicity Standard Handling
          Storage -20°C
          Avoid freeze/thaw Avoid freeze/thaw
          Do not freeze Ok to freeze
          Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          Certificates of Analysis

          TitleLot Number
          438192

          References

          Reference overview
          Mikhailenko, I., et al. 2001. J. Biol. Chem. 276, 39484.
          Rebeck, W.G., et al. 2001. Mol. Brain Res. 87, 238.
          Coukos, G., et al. 1994. Am. J. Pathol. 144, 383.
          Daugherty, A., and Rateri, D.L. 1994. Arterioscler Thromb. 14, 2017.
          Strickland, D.K., et al. 1990. J. Biol. Chem. 265, 17401.

          Brochure

          Title
          Antibody Sourcebook!" Second Edition
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision06-September-2008 JSW
          SynonymsAnti-Low Density Lipoprotein Receptor-Related Protein
          ApplicationFrozen Sections (1-5 µg/ml)
          Immunoblotting (1-5 µg/ml)
          Paraffin Sections (1-5 µg/ml, see application references)
          Application Data
          Detection of light chain LRP by immunoblotting. Samples: Soluble LRP at 500 ng (lane 1) and 50 ng (lane 2) with prestained standard (lane 3). Primary antibody: Anti-LRP, Light Chain Mouse mAb (5A6) (Cat. No. 438192) (1 µg/ml). Detection: chemiluminescence.
          DescriptionPurified mouse monoclonal antibody. Recognizes the ~85 kDa LRP light chain protein under non-reducing conditions.
          BackgroundLRP (Low Density Lipoprotein Receptor-Related Protein) contributes to the pathology of Alzheimer's disease by influencing both the production and clearance of the β-amyloid peptide.
          HostMouse
          Immunogen speciesHuman
          Immunogenpurified, human placenta LRP
          Clone5A6
          IsotypeIgG₂
          Specieshuman, mouse, rabbit
          FormLiquid
          FormulationIn 100 mM NaCl, 50 mM sodium phosphate, 1 mM EDTA, pH 6.6.
          Concentration Label Please refer to vial label for lot-specific concentration
          PreservativeNone
          CommentsVariables associated with assay conditions will dictate the proper working dilution.
          Storage -20°C
          Avoid freeze/thaw
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
          Toxicity Standard Handling
          ReferencesMikhailenko, I., et al. 2001. J. Biol. Chem. 276, 39484.
          Rebeck, W.G., et al. 2001. Mol. Brain Res. 87, 238.
          Coukos, G., et al. 1994. Am. J. Pathol. 144, 383.
          Daugherty, A., and Rateri, D.L. 1994. Arterioscler Thromb. 14, 2017.
          Strickland, D.K., et al. 1990. J. Biol. Chem. 265, 17401.
          Application referencesParaffin Sections Coukos, G., et al. 1994. Am. J. Pathol. 144, 383. Daugherty, A., and Rateri, D.L. 1994. Arterioscler Thromb. 14, 2017. Rebeck, G.W., et al. 1993. Neuron 11, 575.