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ABC107 | Anti-KIF3A Antibody

ABC107
100 µg  
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      Overview

      Replacement Information

      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H ICC Rb Affinity Purified Polyclonal Antibody
      Description
      Catalogue NumberABC107
      DescriptionAnti-KIF3A Antibody
      Alternate Names
      • Kinesin-like protein KIF3A
      • Microtubule plus end-directed kinesin motor 3A
      Background InformationKinesin-like protein KIF3 (KIF3A) is a member of the heteromeric family of kinesins and plays an important role in primary cilia formation. KIF3A functions as a microtubule-based anterograde translocator for membranous organelles and forms a heterotrimeric KIF3 complex with KIF3B or KIF3C and an associated protein, KAP3. Mutations in in KIF3A have been associated with cranial base growth retardation and dysmorphogenesis.
      References
      Product Information
      FormatAffinity Purified
      Control
      • SH-SY5Y cell lysate
      PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Applications
      ApplicationThis Anti-KIF3A Antibody is validated for use in ICC for the detection of KIF3A.
      Key Applications
      • Immunocytochemistry
      Application NotesImmunocytochemistry Analysis: A 1:500 dilution from a representative lot detected KIF3A in A431, HeLa, and NIH/3T3 cells.
      Biological Information
      ImmunogenKLH-conjugated linear peptide corresponding to human KIF3A.
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostRabbit
      Species Reactivity
      • Human
      Species Reactivity NoteDemonstrated to react with Human. Predicted to react with Baboon, Bovine, and Chimpanzee based on 100% sequence homology. Other homologies: Mouse, Rat, Chicken, Zebrafish, and Frog (92% sequence homology).
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • KIF3A
      • KIF3
      Purification MethodAffinity Purfied
      UniProt Number
      Molecular Weight~80 kDa observed
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blot in SH-SY5Y cell lysate.

      Western Blot Analysis: 1 µg/mL of this antibody detected KIF3A in 10 µg of SH-SY5Y cell lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications

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      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies