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MAB5582 | Anti-Iron Regulatory Protein 2 Antibody

100 µL  
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      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H ELISA, WB, IHC M Ascites Monoclonal Antibody
      Catalogue NumberMAB5582
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionAnti-Iron Regulatory Protein 2 Antibody
      Alternate Names
      • IRP2
      • Iron-responsive element-binding protein 2 (IRE-BP2)
      Product Information
      PresentationMouse ascites. Liquid. Contains no preservative.
      ApplicationAnti-Iron Regulatory Protein 2 Antibody detects level of Iron Regulatory Protein 2 & has been published & validated for use in ELISA, WB, IH.
      Key Applications
      • ELISA
      • Western Blotting
      • Immunohistochemistry
      Biological Information
      ImmunogenRecombinant fusion protein.
      SpecificityIRP-2 (Iron Regulatory Protein 2). The antibody reacts with recombinant or native protein. MAB5582 shows no reactivity to IRP1. IRP2 is expressed in very small quantities in normal cells.
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • IREB2
      • IRP2AD
      • ACO3
      • FLJ23381
      • IRP2
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P48200 # Binds to iron-responsive elements (IRES), which are stem-loop structures found in the 5'-UTR of ferritin, and delta aminolevulinic acid synthase mRNAs, and in the 3'-UTR of transferrin receptor mRNA. Binding to the IRE element in ferritin results in the repression of its mRNA translation. Binding of the protein to the transferrin receptor mRNA inhibits the degradation of this otherwise rapidly degraded mRNA.
      COFACTOR: Binds 1 4Fe-4S cluster per subunit (By similarity).
      SIZE: 963 amino acids; 105012 Da
      SIMILARITY: SwissProt: P48200 ## Belongs to the aconitase/IPM isomerase family.
      Physicochemical Information
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.
      Packaging Information
      Material Size100 µL
      Transport Information
      Supplemental Information

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      Life Science Research > Antibodies and Assays > Primary Antibodies