407314 | Anti-Integrin β₃ (Ab-1) Mouse mAb (290.5C10)

407314
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      Overview

      Replacement Information

      Key Specifications Table

      Species ReactivityHostAntibody Type
      H M Monoclonal Antibody

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      407314-100UL
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      Stocked 
      Discontinued
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      Available
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          Will advise
          Contact Customer Service

          Plastic ampoule 100 ul
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          Description
          OverviewRecognizes the β3 integrin subunit in αvβ3 and αllbβ3 integrin protein complexes.
          Catalogue Number407314
          Brand Family Calbiochem®
          SynonymsAnti-CD61
          References
          ReferencesHynes, R.O. 1992. Cell. 69, 11.
          Phillips, D.R., et al. 1991. Cell. 65, 359.
          Albelda, S.M. and Buck, C.A. 1990. FASEB J. 4, 2868.
          Buck, C.A. and Horwitz, A.F. 1987. Ann. Rev. Cell Biol. 3, 179.
          Hynes, R.O. 1987. Cell. 45, 549.
          Product Information
          FormLiquid
          FormulationUndiluted ascites.
          PreservativeNone
          Applications
          Key Applications Immunoprecipitation
          Paraffin Sections
          Enzyme-Linked Immunosorbent Assay
          Flow Cytometry
          Immunoblotting (Western Blotting)
          Application NotesELISA (see comments)
          Flow Cytometry (1:50-1:100)
          Immunoblotting (1:50-1:100)
          Paraffin Sections (1:50-1:100)
          Immunoprecipitation (1:50-1:100)
          Application CommentsThis antibody has also been reported to work for ELISA. Variables associated with assay conditions will dictate the proper working dilution.
          Biological Information
          Immunogenβ₃ integrin from M21 melanoma cells
          ImmunogenHuman
          Clone290.5C10
          HostMouse
          IsotypeIgG₁
          Species Reactivity
          • Human
          Antibody TypeMonoclonal Antibody
          Physicochemical Information
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Dry Ice Only
          Toxicity Standard Handling
          Storage -20°C
          Avoid freeze/thaw Avoid freeze/thaw
          Do not freeze Ok to freeze
          Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          Certificates of Analysis

          TitleLot Number
          407314

          References

          Reference overview
          Hynes, R.O. 1992. Cell. 69, 11.
          Phillips, D.R., et al. 1991. Cell. 65, 359.
          Albelda, S.M. and Buck, C.A. 1990. FASEB J. 4, 2868.
          Buck, C.A. and Horwitz, A.F. 1987. Ann. Rev. Cell Biol. 3, 179.
          Hynes, R.O. 1987. Cell. 45, 549.

          Brochure

          Title
          Antibody Sourcebook!" Second Edition
          The Active Siteル Volume 4, Number 1
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision06-August-2007 RFH
          SynonymsAnti-CD61
          ApplicationELISA (see comments)
          Flow Cytometry (1:50-1:100)
          Immunoblotting (1:50-1:100)
          Paraffin Sections (1:50-1:100)
          Immunoprecipitation (1:50-1:100)
          DescriptionMouse monoclonal antibody supplied as undiluted ascites. Recognizes the β3 integrin subunit in αvβ3 and αllbβ3 integrin protein complexes.
          BackgroundThe integrins are a family of more than 23 heterodimeric transmembrane proteins that mediate cell-cell adhesions as well as cell-substratum adhesions and signal transduction processes. Integrins are heterodimers consisting of noncovalently associated α and β subunits. CD61 non-covalently associates with CD41 (αIlb integrin) and is expressed by megakaryocytes and platelets. The CD61/CD41 complex acts as a receptor for such adhesive ligands as fibronectin, fibrinogen and von Willebrand factor during platelet stimulation.
          HostMouse
          Immunogen speciesHuman
          Immunogenβ₃ integrin from M21 melanoma cells
          Clone290.5C10
          IsotypeIgG₁
          Specieshuman
          FormLiquid
          FormulationUndiluted ascites.
          PreservativeNone
          CommentsThis antibody has also been reported to work for ELISA. Variables associated with assay conditions will dictate the proper working dilution.
          Storage -20°C
          Avoid freeze/thaw
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
          Toxicity Standard Handling
          ReferencesHynes, R.O. 1992. Cell. 69, 11.
          Phillips, D.R., et al. 1991. Cell. 65, 359.
          Albelda, S.M. and Buck, C.A. 1990. FASEB J. 4, 2868.
          Buck, C.A. and Horwitz, A.F. 1987. Ann. Rev. Cell Biol. 3, 179.
          Hynes, R.O. 1987. Cell. 45, 549.