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ABC1485 | Anti-IPR1 Antibody

100 μg  
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      Replacement Information

      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H WB, IHC Rb Affinity Purified Polyclonal Antibody
      Catalogue NumberABC1485
      DescriptionAnti-IPR1 Antibody
      Alternate Names
      • Sp110 nuclear body protein
      • Interferon-induced protein 41/75
      • Speckled 110 kDa
      • Transcriptional coactivator Sp110
      • IPR1
      Background InformationSp110 nuclear body protein, also known as, ;Interferon-induced protein 41/75 or Speckled 110 kDa or Transcriptional coactivator Sp110, and encoded by the gene name IPR1, is a member of the SP100/SP140 family of nuclear body proteins and encodes a leukocyte-specific nuclear body component. Susceptibility to tuberculosis (TB) in mice has recently been attributed to the IPR1 gene. IPR1 can function as an activator of gene transcription and may serve as a nuclear hormone receptor coactivator. IPR1 might play a role in integrating signals generated by intracellular pathogens with mechanisms controlling innate immunity, cell death, and pathogenesis.
      Product Information
      FormatAffinity Purified
      PresentationPurified rabbit polyclonal in buffer containing PBS (pH 7.2) with 0.02% sodium azide.
      ApplicationThis Anti-IPR1 Antibody is validated for use in Western Blotting_x000D_ and Immunohistochemistry for the detection of IPR1.
      Key Applications
      • Western Blotting
      • Immunohistochemistry
      Application NotesImmunohistochemistry Analysis (IHC): 2.5 μg/mL from a representative lot detected IPR1 in human brain tissue.

      Biological Information
      ImmunogenIPR1 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of the human IPR1.
      EpitopeNear C-terminus
      ConcentrationPlease refer to lot specific datasheet.
      Species Reactivity
      • Human
      Antibody TypePolyclonal Antibody
      Gene Symbol
      • SP110
      • IPR1
      Purification MethodAntigen Affinity Purified
      UniProt Number
      Molecular Weight~57 kDa observed. Uncharacterized bands may be observed in some lysate(s).
      Physicochemical Information
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in HeLa cell lysate.

      Western Blotting Analysis (WB): 1 μg/mL of this antibody detected IPR1 in HeLa cell lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 μg
      Transport Information
      Supplemental Information

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      Life Science Research > Antibodies and Assays > Primary Antibodies