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AB15882 | Anti-HuC Antibody

AB15882
100 µg  
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      Overview

      Replacement Information

      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      R, H WB Rb Affinity Purified Polyclonal Antibody
      Description
      Catalogue NumberAB15882
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionAnti-HuC Antibody
      Background InformationHu proteins are mammalian embryonic lethal abnormal visual system (ELAV)-like neuronal RNA-binding proteins that contain three RNA recognition motifs. RNA binding protein HuC promotes neuronal development in both the central and the peripheral nervous systems. HuC antibodies are are also used as markers for developing neurons.
      References
      Product Information
      FormatAffinity Purified
      Control
      • Tested on adult rat brain lysate
      PresentationPurified Antibody in PBS with 0.1% NaN3
      Applications
      ApplicationAnti-HuC Antibody detects level of HuC & has been published & validated for use in WB.
      Key Applications
      • Western Blotting
      Biological Information
      ImmunogenSynthetic peptide near the N-terminus human/rat/mouse HuC.
      EpitopeN-Terminus
      HostRabbit
      SpecificityHuC. By Western blot the antibody reacts with a band at ~ 39 kDa on adult rat brain lysate and rat spinal cord lysate. An additional band at ~ 25 kDa may be seen depending on sample and antibody concentration used.
      Species Reactivity
      • Rat
      • Human
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Entrez Gene SummaryA member of the ELAVL protein family, ELAV-like 3 is a neural-specific RNA-binding protein which contains three RNP-type RNA recognition motifs. The observation that ELAVL3 is one of several Hu antigens (neuronal-specific RNA-binding proteins) recognized by the anti-Hu serum antibody present in sera from patients with paraneoplastic encephalomyelitis and sensory neuronopathy (PEM/PSN) suggests it has a role in neurogenesis. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
      Gene Symbol
      • ELAVL3
      • PLE21
      • HUCL
      • MGC20653
      • HUC
      • HuC
      • DKFZp547J036
      Purification MethodImmunoAffinity Purified
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: Q14576 # May be involved in neuronal differentiation and maintenance.
      SIZE: 367 amino acids; 39547 Da
      TISSUE SPECIFICITY: Brain specific.
      SIMILARITY: SwissProt: Q14576 ## Belongs to the RRM elav family. & Contains 3 RRM (RNA recognition motif) domains.
      Molecular Weight39.5 kDa
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain at 2-8°C in undiluted aliquots for up to 6 months after date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications

      Related Products & Applications

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      Product Families

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      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies