MABE71 Anti-Histone Antibody, Pan, clone F152.C25.WJJ

MABE71
100 µg  
Retrieving price...
Price could not be retrieved
Minimum Quantity needs to be mulitiple of
Upon Order Completion More Information
You Saved ()
 
Request Pricing
Limited AvailabilityLimited Availability
Stocked 
Discontinued
Limited Quantities Available
Available
    Remaining : Will advise
      Remaining : Will advise
      Will advise
      Contact Customer Service
      Contact Customer Service

      Special Offers

       

      Contact Customer Service

      Overview

      Replacement Information

      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, B WB, ELISA M Purified Monoclonal Antibody
      Description
      Catalogue NumberMABE71
      ReplacesMAB052
      DescriptionAnti-Histone Antibody, Pan, clone F152.C25.WJJ
      Alternate Names
      • Histone H1.4
      • Histone H1b
      Background InformationThis antibody detects histone H1 and nuclesomal core proteins histones H2a, H2b, H3, H4. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
      Histone H1 is a nuclear protein necessary for condensation of nucleosome chains into higher order structures.
      References
      Product Information
      FormatPurified
      Control
      • Jurkat cell lysate
      PresentationPurified mouse monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Applications
      ApplicationAnti-Histone Antibody, Pan, clone F152.C25.WJJ is a Mouse Monoclonal Antibody for detection of Histone also known as Histone H1.4, Histone H1b & has been validated in WB, ELISA.
      Key Applications
      • Western Blotting
      • ELISA
      Application NotesELISA Analysis: A representative lot was used by an independent laboratory in ELISA. (Mizoguchi, E., et al. (1997). Gastroenterology. 113:1828-1835.)
      Biological Information
      CloneF152C25W
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostMouse
      IsotypeIgG2aκ
      Species Reactivity
      • Human
      • Bovine
      Antibody TypeMonoclonal Antibody
      Gene Symbol
      • HIST1H1E
      • H1F4
      Purification MethodProtein G
      UniProt Number
      Molecular Weight ~14-33 kDa observed
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blot in Jurkat cell lysate.

      Western Blot Analysis: 0.5 µg/mL of this antibody detected Histone H1 and core proteins on 10 µg of Jurkat cell lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      Anti-Histone Antibody, Pan, clone F152.C25.WJJ SDS

      Title

      Safety Data Sheet (SDS) 

      Anti-Histone Antibody, Pan, clone F152.C25.WJJ Certificates of Analysis

      TitleLot Number
      Anti-Histone, H1 + core proteins, clone -26596342659634
      Anti-Histone, H1 + core proteins, clone -27860412786041
      Anti-Histone, H1 + core proteins, clone -28001742800174
      Anti-Histone, H1 + core proteins, clone F152.C25.W2465294
      Anti-Histone, H1 + core proteins, clone F152.C25.WJJ - 21459972145997
      Anti-Histone, H1 + core proteins, clone F152.C25.WJJ - 24248422424842
      Anti-Histone, H1 + core proteins, clone F152.C25.WJJ - 20427982042798
      Anti-Histone, H1 + core proteins, clone F152.C25.WJJ - 20498032049803
      Anti-Histone, H1 + core proteins, clone F152.C25.WJJ - 22030792203079
      Anti-Histone, H1 + core proteins, clone F152.C25.WJJ - 22071852207185

      References

      Reference overviewPub Med ID
      H3K79 methylation: a new conserved mark that accompanies H4 hyperacetylation prior to histone-to-protamine transition in Drosophila and rat.
      Dottermusch-Heidel, C; Gärtner, SM; Tegeder, I; Rathke, C; Barckmann, B; Bartkuhn, M; Bhushan, S; Steger, K; Meinhardt, A; Renkawitz-Pohl, R
      Biology open  3  444-52  2014

      Show Abstract
      24795146 24795146
      Drosophila protamine-like Mst35Ba and Mst35Bb are required for proper sperm nuclear morphology but are dispensable for male fertility.
      Tirmarche, S; Kimura, S; Sapey-Triomphe, L; Sullivan, W; Landmann, F; Loppin, B
      G3 (Bethesda, Md.)  4  2241-5  2014

      Show Abstract
      25236732 25236732

      Related Products & Applications

      Related Products

      Catalog Number Description  
      05-457 Anti-Histone H1 Antibody, clone AE-4 Show Pricing & Availability
      06-1358 Anti-acetyl (Lys34) phospho (Ser36) Histone H1 Antibody Show Pricing & Availability
      06-1372 Anti-acetyl (Lys26) phospho (Ser27) Histone H1.4 Antibody Show Pricing & Availability
      MAB1276 Anti-Nuclei & Chromosomes Antibody, histone H1 protein, clone 1415-1 Show Pricing & Availability

      Accessories

      Catalog Number Description  
      AP124P Goat Anti-Mouse IgG Antibody, Peroxidase Conjugated, H+L Show Pricing & Availability

      Product Families

      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies