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07-252 | Anti-HMGN2/HMG-17 Antibody

100 µL  
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      Replacement Information

      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      B, H, M, Po, R, Rb ICC, WB Rb Affinity Purified Polyclonal Antibody
      Catalogue Number07-252
      Brand Family Upstate
      Trade Name
      • Upstate
      DescriptionAnti-HMGN2/HMG-17 Antibody
      Product Information
      FormatAffinity Purified
      Presentation0.2M Tris-glycine, pH7.4, 5mg/ml BSA, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30%
      ApplicationDetect HMGN2/HMG-17 with Anti-HMGN2/HMG-17 Antibody (Rabbit Polyclonal Antibody), that has been shown to work in ICC & WB.
      Key Applications
      • Immunocytochemistry
      • Western Blotting
      Biological Information
      ImmunogenRecombinant human HMGN2/HMG-17
      SpecificityHMGN2/HMG-17; slight cross-reactivity with HMGN1/HMG-14
      Species Reactivity
      • Bovine
      • Human
      • Mouse
      • Pig
      • Rat
      • Rabbit
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • HMGN2
      • HMG17
      • MGC5629
      • MGC88718
      Purification MethodImmunoAffinity Purified
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P05204 # Bind to the inner side of the nucleosomal DNA thus altering the interaction between the DNA and the histone octamer. May be involved in the process which maintains transcribable genes in a unique chromatin conformation.
      SIZE: 90 amino acids; 9393 Da
      SIMILARITY: SwissProt: P05204 ## Belongs to the HMGN family.
      Molecular Weight18 kDa
      Physicochemical Information
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality Assuranceroutinely evaluated by immunoblot on acid extracts of murine 10T 1/2 and HeLa cells
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage Conditions1 year at -20°C
      Packaging Information
      Material Size100 µL
      Transport Information
      Supplemental Information


      Certificates of Analysis

      TitleLot Number
      Anti-HMGN2/HMG-17 - 22046 22046
      Anti-HMGN2/HMG-17 - DAM1499873 DAM1499873
      Anti-HMGN2/HMG17 - DAM1825375 DAM1825375


      Reference overviewApplicationPub Med ID
      Nuclear shape changes are induced by knockdown of the SWI/SNF ATPase BRG1 and are independent of cytoskeletal connections.
      Imbalzano, KM; Cohet, N; Wu, Q; Underwood, JM; Imbalzano, AN; Nickerson, JA
      PloS one 8 e55628 2013

      Show Abstract
      Immunofluorescence23405182 23405182
      Specific acetylation of chromosomal protein HMG-17 by PCAF alters its interaction with nucleosomes.
      Herrera, J E, et al.
      Mol. Cell. Biol., 19: 3466-73 (1999) 1999

      Show Abstract
      10207070 10207070
      Chromosomal proteins HMG-14 and HMG-17 are released from mitotic chromosomes and imported into the nucleus by active transport.
      Hock, R, et al.
      J. Cell Biol., 143: 1427-36 (1998) 1998

      Show Abstract
      9852141 9852141

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      Life Science Research > Antibodies and Assays > Primary Antibodies