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ABS1165 | Anti-Glucagon Receptor, N-term Antibody

100 µL  
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      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H WB, IHC Rb Purified Polyclonal Antibody
      Catalogue NumberABS1165
      DescriptionAnti-Glucagon Receptor, N-term Antibody
      Alternate Names
      • Glucagon receptor
      • GL-R
      • Glucagon Receptor
      Background InformationGlucagon is a 29-amino acid peptide that stimulates glycogenolysis and gluconeogenesis in the liver to increase blood glucose. The receptor for glucagon is a class 2 (or class B) GPCR that signals through Gs to stimulate cAMP production. Mice lacking the glucagon receptor have mild hypoglycemia after fasting, and exhibit hyperplasia of pancreatic alpha-cells. Because of its role in promoting hyperglycemia, the glucagon receptor presents a potential target for treatment of diabetes.
      Product Information
      PresentationPurified rabbit polyclonal 1XPBS, 20% Glycerol (pH7), and 0.025% proclin.
      ApplicationAnti-Glucagon Receptor, N-term Antibody is an antibody against Glucagon Receptor for use in Western Blotting, Immunohistochemistry.
      Key Applications
      • Western Blotting
      • Immunohistochemistry
      Application NotesImmunohistochemistry Analysis (IHP): A 1:100 dilution from a representative lot detected Glucagon Receptor in CL1-0 xenograft tissue.
      Biological Information
      ImmunogenSynthetic peptide corresponding to the N-terminus of human Glucagon Receptor.
      ConcentrationPlease refer to lot specific datasheet.
      Species Reactivity
      • Human
      Antibody TypePolyclonal Antibody
      Gene Symbol
      • GCGR
      Purification MethodAntigen Affinity Purified
      UniProt Number
      Molecular Weight~50 kDa observed. Uncharacterized bands may be observed in some lysate(s).
      Physicochemical Information
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in HEK293T cell lysate.

      Western Blotting Analysis (WB): A 1:1,000 dilution of this antibody detected Glucagon Receptor in HEK293T cell lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at -20°C from date of receipt.
      Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
      Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.
      Packaging Information
      Material Size100 µL
      Transport Information
      Supplemental Information

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      Life Science Research > Antibodies and Assays > Primary Antibodies