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06-270 | Anti-Giα3 Antibody

50 µL  
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      Replacement Information

      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, Ht, M, R IP, WB Rb Serum Polyclonal Antibody
      Catalogue Number06-270
      Brand Family Upstate
      Trade Name
      • Upstate
      DescriptionAnti-Giα3 Antibody
      Product Information
      • Widely expressed
      PresentationProtein A Purified immunoglobulin in 30% glycerol, 0.07M Tris-glycine, pH 7.4, 0.105 M NaCl, 0.035% sodium azide as a preservative.
      ApplicationDetect Giα3 using this Anti-Giα3 Antibody validated for use in IP & WB.
      Key Applications
      • Immunoprecipitation
      • Western Blotting
      Biological Information
      Immunogenpeptide corresponding to the C-terminal region of Giα3 (KNNLKECGLY)
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      SpecificityRecognizes Giα3 and Goα; low cross-reactivity with other G-proteins.
      Species Reactivity
      • Human
      • Hamster
      • Mouse
      • Rat
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • GNAI3
      • 87U6
      • G
      • FLJ26559
      • ialpha-3).
      Purification MethodUnpurified
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P08754 # Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. G(k) is the stimulatory G protein of receptor- regulated K(+) channels.
      SIZE: 354 amino acids; 40532 Da
      SUBUNIT: G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site. Interacts with GPSM1 (By similarity).
      SIMILARITY: SwissProt: P08754 ## Belongs to the G-alpha family. G(i/o/t/z) subfamily.
      Molecular Weight40 kDa
      Physicochemical Information
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality Assuranceroutinely evaluated by immunoblot on rat hippocampus membrane preparation, solubilized rat and mouse brain membranes or mouse 3T3/A31 cell lysates
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain for 2 years at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
      Packaging Information
      Material Size50 µL
      Transport Information
      Supplemental Information




      Safety Data Sheet (SDS) 

      Certificates of Analysis

      TitleLot Number
      Anti-Gia3 (rabbit antiserum) - 2149486 2149486
      Anti-Gia3 (rabbit antiserum) - 2281645 2281645
      Anti-Gia3 (rabbit antiserum) - JBC1939898 JBC1939898
      Anti-Gialpha;3 - 0701050671 0701050671
      Anti-Gialpha;3 - 15613 15613
      Anti-Gialpha;3 - 18911 18911
      Anti-Gialpha;3 - 21339 21339
      Anti-Gialpha;3 - 26459 26459
      Anti-Gialpha;3 - DAM1394786 DAM1394786
      Anti-Gialpha;3 - JBC1361876 JBC1361876
      Anti-Gialpha;3 - JBC1363172 JBC1363172
      Anti-Giα3 - 2517341 2517341
      Anti-Giα3 - 2527897 2527897
      Anti-Giα3 -2524068 2524068
      Anti-Giα3 -2608465 2608465
      Anti-Giα3 -2636715 2636715
      Anti-Giα3 -2718326 2718326
      Anti-Giα3 -2762407 2762407


      Reference overviewApplicationPub Med ID
      Subcellular localization of LGN during mitosis: evidence for its cortical localization in mitotic cell culture systems and its requirement for normal cell cycle progression.
      Kaushik, R; Yu, F; Chia, W; Yang, X; Bahri, S
      Molecular biology of the cell 14 3144-55 2003

      Show Abstract Full Text Article
      12925752 12925752
      A role for tyrosine phosphorylation in the regulation and sensitization of adenylate cyclase by melatonin
      Barrett, P., et al
      Faseb J, 14:1619-28 (2000) 2000

      Immunoblotting (Western)10928997 10928997
      Disulfide bonds in the extracellular calcium-polyvalent cation-sensing receptor correlate with dimer formation and its response to divalent cations in vitro
      Ward, D. T., et al
      J Biol Chem, 273:14476-83 (1998) 1998

      Immunoblotting (Western)9603961 9603961
      Apical extracellular calcium/polyvalent cation-sensing receptor regulates vasopressin-elicited water permeability in rat kidney inner medullary collecting duct
      Sands, J. M., et al
      J Clin Invest, 99:1399-405 (1997) 1997

      Immunoblotting (Western)9077550 9077550
      G(o)-protein alpha-subunits activate mitogen-activated protein kinase via a novel protein kinase C-dependent mechanism.
      van Biesen, T, et al.
      J. Biol. Chem., 271: 1266-9 (1996) 1996

      Show Abstract
      Immunoblotting (Western)8576109 8576109
      Guanine nucleotide binding regulatory proteins and adenylate cyclase in livers of streptozotocin- and BB/Wor-diabetic rats. Immunodetection of Gs and Gi with antisera prepared against synthetic peptides.
      Lynch, C J, et al.
      J. Clin. Invest., 83: 2050-62 (1989) 1989

      Show Abstract
      2498395 2498395