AB5016 Anti-GABA (No Gluteraldehyde) Antibody

AB5016
500 µL  
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      Overview

      Replacement Information

      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      R IHC Rb Purified Polyclonal Antibody
      Description
      Catalogue NumberAB5016
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionAnti-GABA (No Gluteraldehyde) Antibody
      References
      Product Information
      FormatPurified
      PresentationPurified immunoglobulin. Liquid in stabilizing buffer (Phosphate buffer with sterile goat serum) containing 0.05% thimerosal.
      Applications
      ApplicationThis Anti-GABA (No Gluteraldehyde) Antibody is validated for use in IH for the detection of GABA (No Gluteraldehyde).
      Key Applications
      • Immunohistochemistry
      Application NotesImmunohistochemistry using silver-intensified immunogold or fluorescence (see recommended protocol). Samples should be fixed with 0.05% - 2.5% glutaraldehyde for optimum detection.

      *This antibody has also been used and found to work with a zero-low glutaraldehyde / high paraformaldehyde fixation (4% paraformaldehyde in 0.1M phosphate buffer / 3% sucrose fixative ). The minimum glutaraldehyde concentration for AB5016 is 0.00%. See protocol that follows. Performance is good with frozen sections, Vibratome sections and tissue culture formats, when penetrating reagents such as 0.3% Triton X-100 are used.

      Optimal working dilutions must be determined by the end user.

      DILUTION: Prepare enough of the AB5016 for your days use by diluting 100X with 1% GSPBT.
      Biological Information
      ImmunogenGABA-glutaraldehyde
      HostRabbit
      SpecificityGABA (gamma-aminobutyrate). The antibody has been calibrated against a spectrum of antigens to assure hapten selectivity and proper affinity. No measurable glutaraldehyde-fixed tissue cross-reactivity (<1:1000) against L-alanine, 1-amino-4-guanidobutane (AGB), D/L-arganine, D/L-aspartate, L-citrulline, L-cysteine, D/L-glutamate, D/L-glutamine, glutathione, glycine, L-lysine, L-ornithine, L-serine, L-threonine, L-tryptophan, L-tyrosine.
      Species Reactivity
      • Rat
      Antibody TypePolyclonal Antibody
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain stock at 2-8°C in undiluted aliquots for up to 6 months. This stock is extremely stable under normal use and routine storage at 2-8°C. Do not freeze this stock.
      Packaging Information
      Material Size500 µL
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      SDS

      Title

      Safety Data Sheet (SDS) 

      Certificates of Analysis

      TitleLot Number
      RABBIT ANTI-GABA2470398
      RABBIT ANTI-GABA POLYCLONAL ANTIBODY - 20917062091706
      RABBIT ANTI-GABA POLYCLONAL ANTIBODY - 21350982135098
      RABBIT ANTI-GABA POLYCLONAL ANTIBODY - 24203552420355
      RABBIT ANTI-GABA -27261302726130
      RABBIT ANTI-GABA -27464842746484
      RABBIT ANTI-GABA POLYCLONAL ANTIBODY2928566
      RABBIT ANTI-GABA POLYCLONAL ANTIBODY2857685
      RABBIT ANTI-GABA POLYCLONAL ANTIBODY3067259
      RABBIT ANTI-GABA POLYCLONAL ANTIBODY - 19926411992641

      References

      Reference overviewApplicationSpeciesPub Med ID
      Retinal amino acid neurochemistry of the southern hemisphere lamprey, Geotria australis.
      Nivison-Smith, L; Collin, SP; Zhu, Y; Ready, S; Acosta, ML; Hunt, DM; Potter, IC; Kalloniatis, M
      PloS one  8  e58406  2013

      Show Abstract
      23516473 23516473
      Neurotransmitter synthesis in poststroke cortical neurogenesis in adult rats.
      Gu, W; Gu, C; Jiang, W; Wester, P
      Stem cell research  4  148-54  2010

      Show Abstract
      20089468 20089468
      Altered expression of retinal molecular markers in the canine RPE65 model of Leber congenital amaurosis.
      Hernández, M; Pearce-Kelling, SE; Rodriguez, FD; Aguirre, GD; Vecino, E
      Investigative ophthalmology & visual science  51  6793-802  2010

      Show Abstract
      ImmunocytochemistryCanine20671290 20671290
      Age-dependent disease expression determines remodeling of the retinal mosaic in carriers of RPGR exon ORF15 mutations.
      Beltran, WA; Acland, GM; Aguirre, GD
      Investigative ophthalmology & visual science  50  3985-95  2009

      Show Abstract Full Text Article
      ImmunohistochemistryCanine19255154 19255154
      Steroids initiate a signaling cascade that triggers rapid sporulation in Dictyostelium.
      Anjard, C; Su, Y; Loomis, WF
      Development (Cambridge, England)  136  803-12  2009

      Show Abstract
      19176583 19176583
      A frameshift mutation in RPGR exon ORF15 causes photoreceptor degeneration and inner retina remodeling in a model of X-linked retinitis pigmentosa.
      Beltran, WA; Hammond, P; Acland, GM; Aguirre, GD
      Investigative ophthalmology & visual science  47  1669-81  2006

      Show Abstract
      ImmunohistochemistryCanine16565408 16565408
      Regulated exocytosis of GABA-containing synaptic-like microvesicles in pancreatic beta-cells.
      Braun, M; Wendt, A; Birnir, B; Broman, J; Eliasson, L; Galvanovskis, J; Gromada, J; Mulder, H; Rorsman, P
      The Journal of general physiology  123  191-204  2004

      Show Abstract
      14769845 14769845

      Data Sheet

      Title
      RABBIT ANTI-GABA POLYCLONAL ANTIBODY