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AB5846 | Anti-GABA A Receptor Associated Protein Antibody

100 µg  
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      Replacement Information

      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, M, R WB Rb Purified Polyclonal Antibody
      Catalogue NumberAB5846
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionAnti-GABA A Receptor Associated Protein Antibody
      Alternate Names
      • GABARAP
      Background InformationGABAA Receptor Associated Protein (GABARAP) interacts with the gamma2 subunit of GABAA Receptors
      Product Information
      PresentationPurified immunoglobulin. Liquid. Buffer = PBS containing 0.02% sodium azide.
      ApplicationThis Anti-GABA A Receptor Associated Protein Antibody is validated for use in WB for the detection of GABA A Receptor Associated Protein.
      Key Applications
      • Western Blotting
      Application NotesImmunoblotting: 1:500-1:1,000. Recognizes a protein of ~14 kDa.

      Optimal working dilutions must be determined by end user.
      Biological Information
      ImmunogenSynthetic peptide from human GABARAP.
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      SpecificityGABA-A Receptor Associated Protein (GABARAP), N-terminus.
      Species Reactivity
      • Human
      • Mouse
      • Rat
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Entrez Gene SummaryGamma-aminobutyric acid A receptors [GABA(A) receptors] are ligand-gated chloride channels that mediate inhibitory neurotransmission. This gene encodes GABA(A) receptor-associated protein, which is highly positively charged in its N-terminus and shares sequence similarity with light chain-3 of microtubule-associated proteins 1A and 1B. This protein clusters neurotransmitter receptors by mediating interaction with the cytoskeleton.
      Gene Symbol
      • GABARAP
      • MM46
      • MGC120155
      • FLJ25768
      • GABA
      • MGC120154
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: O95166 # May play a role in intracellular transport of GABA(A) receptors and its interaction with the cytoskeleton (By similarity).
      SIZE: 117 amino acids; 13918 Da
      SUBUNIT: Interacts with GPHN and NSF (By similarity). Interacts with GABRG2, beta-tubulin and ULK1.
      SUBCELLULAR LOCATION: Intracytoplasmic membrane (By similarity). Cytoplasm, cytoskeleton (By similarity). Note=Largely associated with intracellular membrane structures including the Golgi apparatus and post-synaptic cisternae. Colocalizes with microtubules (By similarity).
      TISSUE SPECIFICITY: Heart, brain, placenta, liver, skeletal muscle, kidney and pancreas.
      SIMILARITY: SwissProt: O95166 ## Belongs to the MAP1 LC3 family.
      Physicochemical Information
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain frozen at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information

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      Life Science Research > Antibodies and Assays > Primary Antibodies