A part of MilliporeSigma

AB15348 | Anti-FMRFamide Antibody

AB15348
50 µL  
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      Overview

      Replacement Information

      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      R IHC Rb Serum Polyclonal Antibody
      Description
      Catalogue NumberAB15348
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionAnti-FMRFamide Antibody
      References
      Product Information
      FormatSerum
      PresentationLiquid with 0.05% sodium azide.
      Applications
      ApplicationAnti-FMRFamide Antibody is an antibody against FMRFamide for use in IH.
      Key Applications
      • Immunohistochemistry
      Application NotesImmunohistochemistry: 1:1,000 - 1:5,000

      Application Notes for Immunohistochemistry:
      - Suggested perfusion steps:
      1) Ca2+-free Tyrode's solution
      2) Paraformaldehyde-picric acid fixative
      3) 10% sucrose in PBS as a cryo-protectant
      - Rapidly dissect tissue and store overnight in 0.1 M phosphate buffer (pH 7.4) containing 10% sucrose.
      - Incubate slide-mounted tissue sections with blocking buffer for 1 hour at room temperature.
      - Remove blocking buffer and incubate the slides with the primary antibody (AB15348 diluted to desired working concentration in blocking buffer) for 18-24 hours at 2-8°C.
      - Remove primary antibody and rinse 3 times in PBS.
      - Incubate sections with fluorescently labeled secondary antibody for 60 minutes at room temperature.

      Optimal working dilutions must be determined by the end user.
      Biological Information
      ImmunogenFMRFamide
      HostRabbit
      SpecificityFMRFamide
      Species Reactivity
      • Rat
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Entrez Gene SummaryFMFRamide-related protein precursor plays a role in the regulation of heart rate and blood pressure and the modulation of morphine-induced antinociception. FMRFAL encodes a preproprotein which is cleaved to form two active peptides with similar function.
      Gene Symbol
      • NPFF
      • FMRFAL
      Purification MethodSerum
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: O15130 # Morphine modulating peptides. Have wide-ranging physiologic effects, including the modulation of morphine-induced analgesia, elevation of arterial blood pressure, and increased somatostatin secretion from the pancreas. Neuropeptide FF potentiates and sensitizes ACCN2 and ACCN3 channels.
      SIZE: 113 amino acids; 12440 Da
      SUBCELLULAR LOCATION: Secreted.
      SIMILARITY: SwissProt: O15130 ## Belongs to the FARP (FMRFamide related peptide) family.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.
      Packaging Information
      Material Size50 µL
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      SDS

      Title

      Safety Data Sheet (SDS) 

      Certificates of Analysis

      TitleLot Number
      RABBIT ANTI- FMRFamide POLYCLONAL ANTIBODY - 2123631 2123631
      RABBIT ANTI- FMRFamide POLYCLONAL ANTIBODY - 2136553 2136553
      RABBIT ANTI- FMRFamide POLYCLONAL ANTIBODY - 2150695 2150695
      RABBIT ANTI- FMRFamide - 2527447 2527447
      RABBIT ANTI- FMRFamide -2548176 2548176
      RABBIT ANTI- FMRFamide -2586532 2586532
      RABBIT ANTI- FMRFamide -2695215 2695215
      RABBIT ANTI- FMRFamide -2761661 2761661
      RABBIT ANTI- FMRFamide POLYCLONAL ANTIBODY - 2839633 2839633
      RABBIT ANTI- FMRFamide POLYCLONAL ANTIBODY - 1990681 1990681
      RABBIT ANTI- FMRFamide POLYCLONAL ANTIBODY - 2043167 2043167
      RABBIT ANTI- FMRFamide POLYCLONAL ANTIBODY - 2191063 2191063

      References

      Reference overviewPub Med ID
      Nervous systems of the sea anemone Nematostella vectensis are generated by ectoderm and endoderm and shaped by distinct mechanisms.
      Nakanishi, N; Renfer, E; Technau, U; Rentzsch, F
      Development (Cambridge, England) 139 347-57 2012

      Show Abstract
      22159579 22159579

      Data Sheet

      Title
      RABBIT ANTI- FMRFamide POLYCLONAL ANTIBODY