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CBL87 | Anti-Endothelin Antibody, CT, clone 3G10

CBL87
1 mg  
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      Overview

      Replacement Information

      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H ICC R Purified Monoclonal Antibody
      Description
      Catalogue NumberCBL87
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionAnti-Endothelin Antibody, CT, clone 3G10
      References
      Product Information
      FormatPurified
      Control
      • Expressed in lung, placental stem villi vessels and in cultured placental vascular smooth muscle cells
      PresentationThe monoclonal is presented at in phosphate buffered saline containing 10mM sodium azide. We recommend that each laboratory determine an optimum working titre for use in its particular application.
      Applications
      ApplicationThis Anti-Endothelin Antibody, C-terminus, clone 3G10 is validated for use in IC for the detection of Endothelin.
      Key Applications
      • Immunocytochemistry
      Application NotesDevelopment of IRMA assays for ET-1 (CBL 85) and ET-3 (CBL 86)

      Suitable for immunocytochemistry on frozen sections

      Optimal working dilutions must be determined by the end user.
      Biological Information
      EpitopeC-terminus
      Clone3G10
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostRat
      SpecificityRecognizes the C-terminal region of all endothelins (amino acid residues 15-21) when used as a capture antibody in IRMA assays. The antibody does not cross-react with "big" endothelin.
      IsotypeIgG2b
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • EDN1
      • OTTHUMP00000039245
      • Preproendothelin-1
      • ET1
      • PPET1
      • ET-1
      • HDLCQ7
      Purification MethodProtein A Purfied
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P05305 # Endothelins are endothelium-derived vasoconstrictor peptides.
      SIZE: 212 amino acids; 24425 Da
      SUBCELLULAR LOCATION: Secreted.
      TISSUE SPECIFICITY: Expressed in lung, placental stem villi vessels and in cultured placental vascular smooth muscle cells.
      SIMILARITY: SwissProt: P05305 ## Belongs to the endothelin/sarafotoxin family.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsFor use within 1 month of purchase store at +4°C, for long term storage aliquot antibody into small volumes and store at -20°C.
      Packaging Information
      Material Size1 mg
      Transport Information
      Supplemental Information
      Specifications

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      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies