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MABT91 | Anti-EB1 Antibody, clone 1A11/4

100 µL  
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      Replacement Information

      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H WB M Purified Monoclonal Antibody
      Catalogue NumberMABT91
      DescriptionAnti-EB1 Antibody, clone 1A11/4
      Alternate Names
      • Microtubule-associated protein RP/EB family member 1
      • APC-binding protein EB1
      • End-binding protein 1
      • EB1
      Background InformationEnd binding protein 1 (EB1) is thought to be associated with adenomatous polyposis coli (APC) and may play a part in regulation of microtubule dynamics in the mammalian cells. EB1 could also play a role in the regulation of microtubule assembly and stability. EB1 is essential for proper cilia assembly in fibroblasts. EB1 has been shown to excite spontaneous nucleation and microtubule growth. APC gene mutation and the loss of negatively regulating WNT signaling is thought to play a role in the proliferation changes of cancer. The loss of association with EB1 could contribute to the development of certain cancers.
      Product Information
      • HeLa cell lysate
      PresentationPurified mouse monoclonal IgG2bκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      ApplicationThis Anti-EB1 Antibody, clone 1A11/4 is validated for use in Western Blotting for the detection of EB1.
      Key Applications
      • Western Blotting
      Biological Information
      ImmunogenRecombinant Protein corresponding to human EB1.
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • MAPRE1
      Purification MethodProtein G Purified
      UniProt Number
      Molecular Weight~30 kDa observed
      Physicochemical Information
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blot in HeLa cell lysate.

      Western Blot Analysis: A 1:1,000 dilution of this antibody detected EB1 in 10 µg of HeLa cell lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µL
      Transport Information
      Supplemental Information




      Safety Data Sheet (SDS) 

      Certificates of Analysis

      TitleLot Number
      Anti-EB1, clone 1A11/4 - Q2058154 Q2058154


      Reference overviewPub Med ID
      EB1 is required for spindle symmetry in mammalian mitosis.
      Brüning-Richardson, A; Langford, KJ; Ruane, P; Lee, T; Askham, JM; Morrison, EE
      PloS one 6 e28884 2011

      Show Abstract
      22216133 22216133

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      Life Science Research > Antibodies and Assays > Primary Antibodies