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ABS763 | Anti-DPAGT1 Antibody

100 µg  
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      Replacement Information

      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      M WB Rb Affinity Purified Polyclonal Antibody
      Catalogue NumberABS763
      DescriptionAnti-DPAGT1 Antibody
      Alternate Names
      • UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase
      Background InformationUDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase, also known as GlcNAc-1-P transferase (G1PT or GPT) or N-acetylglucosamine-1-phosphate transferase, and encoded by the gene name DPAGT1 or DPAGT2, is an enzyme that catalyzes the first step in the dolichol-linked oligosaccharide pathway for glycoprotein biosynthesis. Mutations in this integral endoplasmic reticulum (ER) membrane protein enzyme belongs to the glycosyltransferase family 4 results in the congenital disorder of glycosylation type Ij with symptoms such as severe hypotonia, medically intractable seizures, mental retardation, microcephaly, and exotropia. Recent experiments have shown that DPAGT1 is a target of the Wnt/beta-catenin signaling pathway, with Wnt3a inducing higher DPAGT1 mRNA expression.
      Product Information
      FormatAffinity Purified
      PresentationPurified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.
      ApplicationAnti-DPAGT1 Antibody detects level of DPAGT1 & has been published & validated for use in DPAGT1.
      Key Applications
      • Western Blotting
      Biological Information
      ImmunogenKLH-conjugated synthetic peptide corresponding to the N-terminus of human DPAGT1.
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      Species Reactivity
      • Mouse
      Antibody TypePolyclonal Antibody
      Gene Symbol
      • DPAGT1
      • DPAGT2
      Purification MethodAntigen Affinity Purified
      UniProt Number
      Molecular Weight~42 kDa observed. Uncharacterized bands may be observed in some lysate(s).
      Physicochemical Information
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in mouse kidney tissue lysate with and without blocking peptide.

      Western Blotting Analysis: 1 μg/mL of this antibody detected DPAGT1 in mouse kidney tissue lysate with and without blocking peptide.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information