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07-069 | Anti-Calcineurin/PP2B B Antibody

200 µg  
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      Replacement Information

      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      B, H, M, R IP, WB Rb Purified Polyclonal Antibody
      Catalogue Number07-069
      Brand Family Upstate
      Trade Name
      • Upstate
      DescriptionAnti-Calcineurin/PP2B B Antibody
      Product Information
      Presentation0.1M Tris-glycine, 0.15M NaCl, 0.05% azide before the addition of glycerol to 30%
      ApplicationDetect Calcineurin/PP2B B using this Anti-Calcineurin/PP2B B Antibody validated for use in IP & WB.
      Key Applications
      • Immunoprecipitation
      • Western Blotting
      Biological Information
      ImmunogenRecombinant human Calcineurin/PP2B B expressed in E. coli containing substitutions of Ala for Cys11 and Lys for Cys153
      SpecificityCalcineurin/PP2B B
      Species Reactivity
      • Bovine
      • Human
      • Mouse
      • Rat
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • PPP3R1
      • CNB1
      • CALNB1
      • CNB
      • CNA2
      Purification MethodAmmonium Sulfate Precipitation
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P63098 # Regulatory subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase. Confers calcium sensitivity.
      SIZE: 170 amino acids; 19300 Da
      SUBUNIT: Composed of a catalytic subunit (A) and a regulatory subunit (B).
      SIMILARITY: SwissProt: P63098 ## Contains 4 EF-hand domains.
      MISCELLANEOUS: This protein has four functional calcium-binding sites.
      Molecular Weight19kDa
      Physicochemical Information
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality Assuranceroutinely evaluated by immunoblot on rat brain cytosol preparation
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage Conditions2 years at -20°C
      Packaging Information
      Material Size200 µg
      Transport Information
      Supplemental Information




      Safety Data Sheet (SDS) 

      Certificates of Analysis

      TitleLot Number
      Anti-Calcineurin/PP2B B - 20011 20011
      Anti-Calcineurin/PP2B B - 23618 23618
      Anti-Calcineurin/PP2B B - 26690 26690


      Reference overviewPub Med ID
      Chronic psychosocial stress triggers cognitive impairment in a novel at-risk model of Alzheimer's disease.
      Tran TT, Srivareerat M, Alkadhi KA
      Neurobiology of disease 37 756-63. Epub 2010 Jan 4. 2010

      Show Abstract
      20044001 20044001
      Regulation of calcineurin activity in insulin-secreting cells: stimulation by Hsp90 during glucocorticoid-induced apoptosis.
      Felicia Ranta,Martina Düfer,Björn Stork,Sebastian Wesselborg,Gisela Drews,Hans-Ulrich Häring,Florian Lang,Susanne Ullrich
      Cellular signalling 20 2008

      Show Abstract
      18611438 18611438
      Differential calcineurin signalling activity and regeneration efficacy in diaphragm and limb muscles of dystrophic mdx mice.
      Nicole Stupka, Belinda J Michell, Bruce E Kemp, Gordon S Lynch
      Neuromuscular disorders : NMD 16 337-46 2006

      Show Abstract
      16621557 16621557
      The calcineurin signal transduction pathway is essential for successful muscle regeneration in mdx dystrophic mice.
      Nicole Stupka, Paul Gregorevic, David R Plant, Gordon S Lynch
      Acta neuropathologica 107 299-310 2004

      Show Abstract
      14727129 14727129

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      Life Science Research > Antibodies and Assays > Primary Antibodies