05-187 | Anti-Calcineurin/PP2B Antibody, β subunit, clone VA1

05-187
50 µg  
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      Overview

      Replacement Information

      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      Vrt ELISA, ICC, IP, WB M Purified Monoclonal Antibody
      Description
      Catalogue Number05-187
      Brand Family Upstate
      Trade Name
      • Upstate
      DescriptionAnti-Calcineurin/PP2B Antibody, β subunit, clone VA1
      References
      Product Information
      FormatPurified
      Presentation0.1M Tris-glycine, pH 7.4, 0.15M NaCl, containing 0.05% sodium azide
      Applications
      ApplicationThis Anti-Calcineurin/PP2B Antibody, β subunit, clone VA1 is validated for use in ELISA, IC, IP, WB for the detection of Calcineurin/PP2B.
      Key Applications
      • ELISA
      • Immunocytochemistry
      • Immunoprecipitation
      • Western Blotting
      Biological Information
      ImmunogenPurified bovine PP2B
      CloneVA1
      HostMouse
      Specificityregulatory (β) subunit of calcineurin
      IsotypeIgG
      Species Reactivity
      • Vertebrates
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • PPP3R1
      • CNB1
      • CALNB1
      • CNB
      • CNA2
      Purification MethodDEAE chromatography, Affinity Gel blue
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P63098 # Regulatory subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase. Confers calcium sensitivity.
      SIZE: 170 amino acids; 19300 Da
      SUBUNIT: Composed of a catalytic subunit (A) and a regulatory subunit (B).
      SIMILARITY: SwissProt: P63098 ## Contains 4 EF-hand domains.
      MISCELLANEOUS: This protein has four functional calcium-binding sites.
      Molecular Weight19 kDa
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality Assuranceroutinely evaluated in rabbit, rat and bovine brain extracts
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage Conditions2 years at -20°C
      Packaging Information
      Material Size50 µg
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      SDS

      Title

      Safety Data Sheet (SDS) 

      Certificates of Analysis

      TitleLot Number
      Anti-Calcineurin/ PP2B #223;, clone VA1 (mouse monoclonal IgG) - DAM1437252 DAM1437252
      Anti-Calcineurin/PP2B, beta;subunit, clone VA1 - 13787 13787
      Anti-Calcineurin/PP2B, beta;subunit, clone VA1 - 20582 20582

      References

      Reference overviewApplicationPub Med ID
      Association of protein kinase A and protein phosphatase 2B with a common anchoring protein
      Coghlan, V. M., et al
      Science, 267:108-11 (1995)  1995

      Immunoblotting (Western)7528941 7528941
      Demonstration of different metal ion-induced calcineurin conformations using a monoclonal antibody.
      Matsui, H, et al.
      J. Biol. Chem., 260: 4174-9 (1985)  1985

      Show Abstract
      2984195 2984195

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      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies