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MABS761 | Anti-CLPP, clone EPR7133, Rabbit Monoclonal Antibody

MABS761
100 µL  
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      Overview

      Replacement Information

      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H WB, FC Rb Unpurified Monoclonal Antibody
      Description
      Catalogue NumberMABS761
      DescriptionAnti-CLPP, clone EPR7133, Rabbit Monoclonal Antibody
      Alternate Names
      • Putative ATP-dependent Clp protease proteolytic subunit, mitochondrial
      • Endopeptidase ClpP1
      • pClpP
      Background InformationPutative ATP-dependent Clp protease proteolytic subunit, mitochondrial, also known as Endopeptidase Clp, and encoded by the gene name CLPP, belongs to the peptidase family S14 and hydrolyzes proteins into small peptides in the presence of ATP and magnesium. CLPP is transported into mitochondrial matrix and is associated with the inner mitochondrial membrane. CLPP may be responsible for a fairly general and central housekeeping function rather than for the degradation of specific substrates.
      References
      Product Information
      FormatUnpurified
      PresentationRabbit monoclonal in buffer containing PBS with up to 0.1% sodium azide, 0.05% BSA, and 50% glycerol.
      Applications
      ApplicationAnti-CLPP, clone EPR7133, Rabbit Monoclonal is an antibody against CLPP for use in WB, FC.
      Key Applications
      • Western Blotting
      • Flow Cytometry
      Application NotesFlow Cytometry Analysis: A 1:10-100 dilution from a representative lot detected CLPP in K562 cells.

      Produced in collaboration with Epitomics™
      Biological Information
      ImmunogenSynthetic peptide corresponding to human CLPP.
      CloneEPR7133
      ConcentrationPlease refer to lot specific datasheet.
      HostRabbit
      IsotypeIgG
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Gene Symbol
      • CLPP
      Purification MethodUnpurified
      UniProt Number
      Molecular Weight~26 kDa observed. Uncharacterized bands may be observed in some lysate(s).
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in human fetal muscle, Saos-2, A431, HEK293, K562, and A549 lysates.

      Western Blotting Analysis: A 1:1,000-10,000 dilution of this antibody detected CLPP in human fetal muscle, Saos-2, A431, HEK293, K562, and A549 lysates.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at -20°C from date of receipt.
      Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
      Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.
      Packaging Information
      Material Size100 µL
      Transport Information
      Supplemental Information
      Specifications

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      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies