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ABE704 | Anti-CKAP5 Antibody

100 µL  
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      Replacement Information

      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H IHC, ICC Rb Affinity Purified Polyclonal Antibody
      Catalogue NumberABE704
      DescriptionAnti-CKAP5 Antibody
      Alternate Names
      • Cytoskeleton-associated protein 5
      • Colonic and hepatic tumor overexpressed gene protein
      • Ch-TOG
      • CKAP5
      Background InformationCytoskeleton-associated protein 5 (CKAP5) is a member of the TOG/XMAP215 family containing heat repeats and plays a role in kinetochore mircotubule protection from depolymerization by MCAK. CKAP5 is the homolog of the Xenopus protein, XMAP25 (also known as chTog), which plays an essential role in centrosomal assembly. CKAP5 is localized in the perinuclear cytoplasm during interphase and at the spindle poles and centrosomes during mitosis. Studies show CKAP5 interacts with TACC1, TACC3, and tubulin leading to the hypothesis that it functions in spindle microtuble organization. Hepatomas and colonic tumors have shown overexpression of CKAP5.
      Product Information
      FormatAffinity Purified
      PresentationPurified rabbit polyclonal in buffer containing PBS (pH 7.2) with 0.02% sodium azide and 40% glycerol.
      ApplicationAnti-CKAP5 Antibody is an antibody against CKAP5 for use in Immunohistochemistry, Immunocytochemistry.
      Key Applications
      • Immunohistochemistry
      • Immunocytochemistry
      Application NotesImmunocytochemistry Analysis (ICC): 1-4 μg/mL from a representative lot detected CKAP5 in A431 cells.

      Biological Information
      ImmunogenRecombinant protein corresponding to human CKAP5.
      ConcentrationPlease refer to lot specific datasheet.
      Species Reactivity
      • Human
      Antibody TypePolyclonal Antibody
      Gene Symbol
      • CKAP5
      Purification MethodAffinity
      UniProt Number
      Molecular Weight225 kDa calculated
      Physicochemical Information
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceImmunohistochemistry Analysis (IHC): A 1:500-1000 dilution from a representative lot detected CKAP5 in human pancreas tissue.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at -20°C from date of receipt.
      Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
      Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.
      Packaging Information
      Material Size100 µL
      Transport Information
      Supplemental Information

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      Life Science Research > Antibodies and Assays > Primary Antibodies