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MABN682 | Anti-CDKN1C, clone 3 E3 Antibody

100 µL  
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      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H WB M Ascites Monoclonal Antibody
      Catalogue NumberMABN682
      DescriptionAnti-CDKN1C, clone 3 E3 Antibody
      Alternate Names
      • Cyclin-dependent kinase inhibitor 1C
      • Cyclin-dependent kinase inhibitor p57
      • p57Kip2
      • CDKN1C
      Background InformationThe protein encoded by this gene is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene. CDKN1C is expressed in the heart, brain, lung, skeletal muscle, kidney, pancreas and testis. High levels are seen in the placenta while low levels are seen in the liver.
      Product Information
      PresentationMouse monoclonal IgG1 ascitic fluid containing 0.03% sodium azide. 
      Key Applications
      • Western Blotting
      Biological Information
      ImmunogenPurified recombinant fragment of human CDKN1C expressed in E. Coli.
      Clone3 E3
      ConcentrationPlease refer to lot specific datasheet.
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Gene Symbol
      • CDKN1C
      • KIP2
      Purification MethodUnpurified
      UniProt Number
      Molecular Weight~65 kDa observed. Uncharacterized bands may be observed in some lysate(s).
      Physicochemical Information
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in HEK293 and CDKN1C-hIgGFc transfected HEK293 cell lysate.

      Western Blotting Analysis (WB): A 1:500-2,000 dilution of this antibody detected CDKN1C in hIgGFc transfected HEK293 cell lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at -20°C from date of receipt.
      Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
      Packaging Information
      Material Size100 µL
      Transport Information
      Supplemental Information

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      Life Science Research > Antibodies and Assays > Primary Antibodies