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MABF582 | Anti-CD44 Antibody (human/mouse), PE-Cy5, clone IM7

MABF582
25 µg  
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      Overview

      Replacement Information

      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, M FC, IHC, IP, WB R PE-Cy5 Monoclonal Antibody
      Description
      Catalogue NumberMABF582
      DescriptionAnti-CD44 Antibody (human/mouse), PE-Cy5, clone IM7
      Alternate Names
      • CD44 antigen
      • Extracellular matrix receptor III
      • ECMR-III
      • GP90 lymphocyte homing/adhesion receptor
      • HUTCH-I
      • Hermes antigen
      • Hyaluronate receptor
      • Lymphocyte antigen 24
      • Ly-24
      • Phagocytic glycoprotein 1
      • PGP-1
      • Phagocytic glycoprotein I
      • PGP-I
      • CD44
      Background InformationThe IM7 antibody recognizes CD44, a ubiquitously expressed cell surface receptor which is important for extracellular matrix organization, cell-cell and cell-matrix adhesion and migration. CD44 may be expressed in a number of different isoforms (splice variants) from the most typical or “standard” form, known as CD44s, to variants designated CD44v, e.g. CD44v1 or CD44v6. These receptors interact with several ligands, but most often associate with an extracellular matrix component hyaluronate, throµgh which it mediates adhesion.The IM7 antibody may be used for detection of all isoforms of CD44, as it recognizes constant epitopes near the extracellular proximal domain. (Xu et al, 2002, J. Leukoc. Biol. 72:1133-1141). It has been reported to be cross-reactive with many non-human species including Baboon, Chimpanzee, Cynomolgus, Rhesus, Horse, Cow, Pig, Dog and Cat CD44.
      References
      Product Information
      FormatPE-Cy5
      PresentationPurified Rat Monoclonal Antibody in buffer containing 10 mM NaH2PO4, 150 mM NaCl, 0.1% gelatin, pH 7.2, and up to 0.1% sodium azide.
      Applications
      ApplicationThis rat monoclonal antibody Anti-CD44 (human/mouse), PE-Cy5, clone IM7 validated for use in western blotting, IP, IHC & Flow Cytometry for the detection of CD44.
      Key Applications
      • Flow Cytometry
      • Immunohistochemistry
      • Immunoprecipitation
      • Western Blotting
      Biological Information
      ImmunogenImmunogen information for this antibody is proprietary information.
      CloneIM7
      Concentration0.2 mg/mL
      HostRat
      IsotypeIgG2bκ
      Species Reactivity
      • Human
      • Mouse
      Antibody TypeMonoclonal Antibody
      Gene Symbol
      • Cd44
      • Ly-24
      Purification MethodSize Exclusion Chromatography
      UniProt Number
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceThe monoclonal antibody was purified from tissue culture supernatant via affinity chromatography. The purified antibody was conjugated under optimal conditions, with unreacted dye removed from the preparation.

      Flow Cytometry Analysis: 0.125 µg of this antibody detected CD44 in one million C57Bl/6 splenocytes.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsIt is recommended to store the product undiluted at 2-8°C and protected from prolonged exposure to light. Do not freeze.
      Packaging Information
      Material Size25 µg
      Transport Information
      Supplemental Information
      Specifications

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      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies