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MABF336 | Anti-CD123 (human) Antibody, FITC, clone 6H6

100 tests  
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      Replacement Information

      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H FC, WB, IHC, IP M FITC Monoclonal Antibody
      Catalogue NumberMABF336
      DescriptionAnti-CD123 (human) Antibody, FITC, clone 6H6
      Alternate Names
      • Interleukin-3 receptor subunit alpha
      • IL-3 receptor subunit alpha
      • IL-3R subunit alpha
      • IL-3R-alpha
      • IL-3RA
      • CD123
      Background InformationInterleukin-3 receptor subunit alpha (IL3RA), also known as CD123 or IL-3R subunit alpha or IL-3R alpha or IL-3RA is a single-pass type 1 membrane protein that belongs to the type 1 cytokine receptor family. CD123 is a receptor for Interleukin 3. The binding of CD123 to IL3 is dependent on the beta subunit. The beta subunit is activated by the ligand binding and is required for the biological activities of IL3. CD123 is expressed by myeloid precursors, macrophages, dendritic cells, mast cells, basophils, megakaryocytes, and some B cells.
      Product Information
      PresentationPurified mouse conjugate antibody in buffer containing PBS (pH 7.2) with up to 0.1% sodium azide and 0.2% (w/v) BSA.
      ApplicationDetect IL-3 Receptor using this mouse monoclonal antibody, Anti-CD123 (human) Antibody, FITC, clone 6H6 validated for use in Flow Cytometry, western blotting, IHC & IP.
      Key Applications
      • Flow Cytometry
      • Western Blotting
      • Immunohistochemistry
      • Immunoprecipitation
      Application NotesWestern Blotting Analysis: A representative lot detected human CD123 in Western Blotting. (Sun Q, et al. 1996.)

      Immunohistochemistry Analysis: A representative lot detected human CD123 in Immunohistochemistry. (Herling M, et al. 2003.)

      Immunoprecipitation Analysis: A representative lot detected human CD123 in Immunoprecipitation. (Sun Q, et al. 1996.)

      Biological Information
      ImmunogenHuman CD123 (IL-3Rα) transfected COS cells.
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      SpecificityThis antibody does not inhibit IL-3 binding to low- or high-affinity IL-3 receptors.
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Gene Symbol
      • 3RA
      • IL3R
      Purification MethodAffinity
      UniProt Number
      Molecular Weight43 kDa calculated
      Physicochemical Information
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceThe antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions. The solution is free of unconjugated FITC and unconjugated antibody.

      Flow Cytometry Analysis: 5 μL of this antibody detected CD123 in one million human peripheral blood leukocytes.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsThe antibody solution should be stored undiluted at 2-8°C and protected from prolonged exposure to light. Do not freeze.
      Packaging Information
      Material Size100 tests
      Transport Information
      Supplemental Information

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      Life Science Research > Antibodies and Assays > Primary Antibodies