A part of MilliporeSigma

04-1590 | Anti-CCR9 Antibody, clone 9B1

04-1590
100 µg  
Retrieving price...
Price could not be retrieved
Minimum Quantity needs to be mulitiple of
Upon Order Completion More Information
You Saved ()
 
Request Pricing
Limited AvailabilityLimited Availability
Stocked 
Discontinued
Limited Quantities Available
Available
    Remaining : Will advise
      Remaining : Will advise
      Will advise
      Contact Customer Service

      Special Offers

       

      Contact Customer Service

      Click To Print This Page

      Overview

      Replacement Information

      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      M FC R Purified Monoclonal Antibody
      Description
      Catalogue Number04-1590
      DescriptionAnti-CCR9 Antibody, clone 9B1
      Alternate Names
      • chemokine (C-C motif) receptor 9
      • CDw199 antigen
      • G-protein coupled receptor 28
      • G protein-coupled receptor 28
      Background InformationCCR9 (chemokine receptor 9) is a chemokine receptor that is expressed in thymocytes and T lymphocytes from the small intestine and colon but not in lymphocytes from tonsils, lung, inflamed liver, normal or inflamed skin, inflamed synovium and synovial fluid, breast milk, and seminal fluid (Kunkel et al., 2000). CCR9 is not detected in natural killer cells, monocytes, eosinophils, basophils, and neutrophils. CCR9 binds TECK (thymus-expressed chemokine), a CC chemokine expressed in thymus and small intestine. TECK chemoattracts dendritic cells, thymocytes, and activated macrophages.
      References
      Product Information
      FormatPurified
      Control
      • CD8+ mouse thymocytes
      PresentationPurified rat monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.05% sodium azide.
      Applications
      ApplicationDetect CCR9 using this Anti-CCR9 Antibody, clone 9B1 validated for use in FC.
      Key Applications
      • Flow Cytometry
      Biological Information
      ImmunogenKLH-conjugated linear peptide corresponding to the N-terminus of mouse CCR9.
      EpitopeN-terminus
      Clone9B1
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostRat
      SpecificityThis antibody recognizes CCR9 at the N-terminus.
      IsotypeIgG2aκ
      Species Reactivity
      • Mouse
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • CCR9
      • GPR28
      • CC-CKR-9
      • D6
      • GPR-9-6
      • CCR10
      • CCR-9
      • CMKBR9
      • CCBP2
      Purification MethodProtein G Purified
      UniProt Number
      UniProt SummaryFUNCTION: Receptor for chemokine SCYA25/TECK. Subsequently transduces a signal by increasing the intracellular calcium ions level.

      SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.

      TISSUE SPECIFICTY: Highly expressed in the thymus and low in lymph nodes and spleen.

      SEQUENCE SIMILARITIES: Belongs to the G-protein coupled receptor 1 family.
      Molecular Weight~42 kDa (expected MW)
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Flow Cytometry in CD8+ mouse thymocytes.

      Flow Cytometry Analysis: 1 µg of this antibody detected CCR9 in CD8+ mouse thymocytes.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications