A part of MilliporeSigma

04-1590 | Anti-CCR9 Antibody, clone 9B1

100 µg  
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      Replacement Information

      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      M FC R Purified Monoclonal Antibody
      Catalogue Number04-1590
      DescriptionAnti-CCR9 Antibody, clone 9B1
      Alternate Names
      • chemokine (C-C motif) receptor 9
      • CDw199 antigen
      • G-protein coupled receptor 28
      • G protein-coupled receptor 28
      Background InformationCCR9 (chemokine receptor 9) is a chemokine receptor that is expressed in thymocytes and T lymphocytes from the small intestine and colon but not in lymphocytes from tonsils, lung, inflamed liver, normal or inflamed skin, inflamed synovium and synovial fluid, breast milk, and seminal fluid (Kunkel et al., 2000). CCR9 is not detected in natural killer cells, monocytes, eosinophils, basophils, and neutrophils. CCR9 binds TECK (thymus-expressed chemokine), a CC chemokine expressed in thymus and small intestine. TECK chemoattracts dendritic cells, thymocytes, and activated macrophages.
      Product Information
      • CD8+ mouse thymocytes
      PresentationPurified rat monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.05% sodium azide.
      ApplicationDetect CCR9 using this Anti-CCR9 Antibody, clone 9B1 validated for use in FC.
      Key Applications
      • Flow Cytometry
      Biological Information
      ImmunogenKLH-conjugated linear peptide corresponding to the N-terminus of mouse CCR9.
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      SpecificityThis antibody recognizes CCR9 at the N-terminus.
      Species Reactivity
      • Mouse
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • CCR9
      • GPR28
      • CC-CKR-9
      • D6
      • GPR-9-6
      • CCR10
      • CCR-9
      • CMKBR9
      • CCBP2
      Purification MethodProtein G Purified
      UniProt Number
      UniProt SummaryFUNCTION: Receptor for chemokine SCYA25/TECK. Subsequently transduces a signal by increasing the intracellular calcium ions level.

      SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.

      TISSUE SPECIFICTY: Highly expressed in the thymus and low in lymph nodes and spleen.

      SEQUENCE SIMILARITIES: Belongs to the G-protein coupled receptor 1 family.
      Molecular Weight~42 kDa (expected MW)
      Physicochemical Information
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Flow Cytometry in CD8+ mouse thymocytes.

      Flow Cytometry Analysis: 1 µg of this antibody detected CCR9 in CD8+ mouse thymocytes.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information