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MABS420 | Anti-CACYBP, clone 7D11 Antibody

MABS420
100 µL  
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      Overview

      Replacement Information

      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H IHC M Purified Monoclonal Antibody
      Description
      Catalogue NumberMABS420
      DescriptionAnti-CACYBP, clone 7D11 Antibody
      Alternate Names
      • Calcyclin-binding protein
      • CacyBP
      • hCacyBP
      • S100A6-binding protein
      • Siah-interacting protein
      Background InformationCalcyclin-binding protein, also known as CacyBP, hCacyBP, S100A6-binding protein, Siah-interacting protein, and encoded by the gene name CACYBP/ S100A6BP/ SIP is a member of the S100 family of proteins containing 2 EF-hand calcium-binding morifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. CACYBP may function in stimulation of Ca2+-dependent insulin release, stimulation of prolactin secretion, and exocytosis. Chromosomal rearrangements and altered expression of this gene have been implicated in melanoma.
      References
      Product Information
      FormatPurified
      PresentationPurified mouse monoclonal IgG1 in buffer containing PBS with up to 0.1% sodium azide.
      Applications
      ApplicationAnti-CACYBP, clone 7D11 Antibody detects level of CACYBP & has been published & validated for use in CACYBP.
      Key Applications
      • Immunohistochemistry
      Biological Information
      ImmunogenPurified recombinant fragment of human CACYBP expressed in E. Coli
      Clone7D11
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostMouse
      IsotypeIgG1
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Gene Symbol
      • CACYBP
      • S100A6BP
      • SIP
      Purification MethodProtein G Purified
      UniProt Number
      Molecular Weight26 kDa calculated
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceImmunohistochemistry Analysis: A 1:200-1,000 dilution from a representative lot detected CACYBP in human brain glioma tissue.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µL
      Transport Information
      Supplemental Information
      Specifications