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07-272 | Anti-Arp3 Antibody

100 µL  
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      Replacement Information

      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      B, H, M WB Rb Affinity Purified Polyclonal Antibody
      Catalogue Number07-272
      Brand Family Upstate
      Trade Name
      • Upstate
      DescriptionAnti-Arp3 Antibody
      Product Information
      FormatAffinity Purified
      Presentation0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide, 5mg/ml BSA before the addition of glycerol to 30%
      ApplicationThis Anti-Arp3 Antibody is validated for use in WB for the detection of Arp3.
      Key Applications
      • Western Blotting
      Biological Information
      Immunogenpeptide corresponding to amino acids 400-418 (C-YEEIGPSIVRHNPVFGVMS) of human Arp3 (actin like protein 3)
      Species Reactivity
      • Bovine
      • Human
      • Mouse
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Entrez Gene SummaryThe specific function of this gene has not yet been determined; however, the protein it encodes is known to be a major constituent of the ARP2/3 complex. This complex is located at the cell surface and is essential to cell shape and motility through lamellipodial actin assembly and protrusion.
      Gene Symbol
      • ACTR3
      • ARP3
      Purification MethodImmunoaffinity Chromatography
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P61158 # Functions as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the pointed end of the daughter actin filament.
      SIZE: 418 amino acids; 47371 Da
      SUBUNIT: Component of the Arp2/3 complex composed of ARP2, ARP3, ARPC1B/p41-ARC, ARPC2/p34-ARC, ARPC3/p21-ARC, ARPC4/p20-ARC and ARPC5/p16-ARC.
      SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton.
      SIMILARITY: SwissProt: P61158 ## Belongs to the actin family. ARP3 subfamily.
      Molecular Weight50kDa
      Physicochemical Information
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality Assuranceroutinely evaluated by immunoblot on lysates from 3T3/A31, A431, HeLa, Jurket, Raji, CTLL, L6, or PC-12 cells
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage Conditions1 year at -20°C
      Packaging Information
      Material Size100 µL
      Transport Information
      Supplemental Information




      Safety Data Sheet (SDS) 

      Certificates of Analysis

      TitleLot Number
      Anti-Arp3 (rabbit immunoaffinity purified IgG) - 1982618 1982618
      Anti-Arp3 (rabbit immunoaffinity purified IgG) - 2225239 2225239
      Anti-Arp3 (rabbit immunoaffinity purified IgG) - 2297231 2297231
      Anti-Arp3 (rabbit immunoaffinity purified IgG) - DAM1429991 DAM1429991
      Anti-Arp3 (rabbit immunoaffinity purified IgG) - JBC1938966 JBC1938966
      Anti-Arp3 - 2056627 2056627
      Anti-Arp3 - 22110 22110
      Anti-Arp3 - 32648 32648
      Anti-Arp3 - DAM1437142 DAM1437142
      Anti-Arp3 -2645299 2645299
      Anti-Arp3 -2700824 2700824
      Anti-Arp3 -2800181 2800181


      Reference overviewApplicationPub Med ID
      An image-based, dual fluorescence reporter assay to evaluate the efficacy of shRNA for gene silencing at the single-cell level.
      Kojima, S; Borisy, GG
      F1000Research 3 60 2014

      Show Abstract
      Western Blotting24741441 24741441
      Characterization of the metastasis-associated protein, S100A4. Roles of calcium binding and dimerization in cellular localization and interaction with myosin.
      Edward J Kim, David M Helfman
      The Journal of biological chemistry 278 30063-73 2003

      Show Abstract
      Immunocytochemistry12756252 12756252
      Actin polymerization is induced by Arp2/3 protein complex at the surface of Listeria monocytogenes.
      Welch, M D, et al.
      Nature, 385: 265-9 (1997) 1997

      Show Abstract
      9000076 9000076
      The human Arp2/3 complex is composed of evolutionarily conserved subunits and is localized to cellular regions of dynamic actin filament assembly.
      Welch, M D, et al.
      J. Cell Biol., 138: 375-84 (1997) 1997

      Show Abstract
      9230079 9230079

      Technical Info

      Fluorescent Gelatin Degradation Assays for Investigating Invadopodia Formation

      Newsletters / Publications

      Cellutions Newsletter: 2011, Vol. 2

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      Life Science Research > Antibodies and Assays > Primary Antibodies