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AB15568-50UL | Anti-Aquaporin 7 Antibody

AB15568-50UL
50 µL  
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      Overview

      Replacement Information

      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      M, R ICC, IHC, WB Rb Purified Polyclonal Antibody
      Description
      Catalogue NumberAB15568-50UL
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionAnti-Aquaporin 7 Antibody
      Alternate Names
      • AQP7
      References
      Product Information
      FormatPurified
      Control
      • Included free of charge with the antibody is 40 μg of control antigen (lyophilized powder). The stock solution of the antigen can be made up using 100 μL of sterile deionized water. For negative control, preincubate 1 μg of peptide with 1 μg of antibody for one hour at room temperature. Optimal concentrations must be determined by the end user.
      PresentationLyophilized from phosphate buffered saline, pH 7.4, containing 1% BSA, and 0.05% sodium azide as a preservative. Reconstitute with 50 μL of sterile deionized water. Centrifuge antibody preparation before use (10,000 xg for 5 min).
      Applications
      ApplicationAnti-Aquaporin 7 Antibody detects level of Aquaporin 7 & has been published & validated for use in IC, IH & WB.
      Key Applications
      • Immunocytochemistry
      • Immunohistochemistry
      • Western Blotting
      Application NotesWestern blot: 1:200-1:600 using ECL on rat and mouse kidney membrane lysate.
      Immunohistochemistry on rat testis sections.
      Immunocytochemistry: 1:800 using 3T3-L1 adipocytes.
      Dilutions should be made using a carrier protein such as BSA (1-3%).
      Optimal working dilutions must be determined by the end user.
      Biological Information
      ImmunogenPurified peptide from the N-terminus of rat AQP7 (Accession number P56403).
      HostRabbit
      SpecificityRecognizes Aquaporin 7 (AQP7).
      Species Reactivity
      • Mouse
      • Rat
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Entrez Gene SummaryAquaporins/major intrinsic protein (MIP) are a family of water-selective membrane channels. Aquaporin 7 has greater sequence similarity with AQP3 and AQP9 and they may be a subfamily. Aquaporin 7 and AQP3 are at the same chromosomal location suggesting that 9p13 may be a site of an aquaporin cluster. Aquaporin 7 facilitates water, glycerol and urea transport. It may play an important role in sperm function.
      Gene Symbol
      • AQP7
      • Aquaporin-7-like
      • AQP-7
      • AQPap
      • AQP9
      • MGC149555
      • Aquaporin-7
      • MGC149556
      • AQP7L
      Purification MethodImmunoAffinity Purified
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: O14520 # Forms a channel for water and glycerol.
      SIZE: 342 amino acids; 37232 Da
      SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
      DOMAIN: SwissProt: O14520 Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro/Ala-Ala/Ser (NPA).
      SIMILARITY: Belongs to the MIP/aquaporin (TC 1.A.8) family.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain lyophilized material at -20°C for up to 12 months after date of receipt. After reconstitution maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.
      Packaging Information
      Material Size50 µL
      Transport Information
      Supplemental Information
      Specifications

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      Alternative Packsize

      Catalog Number Description  
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      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies