A part of MilliporeSigma

ABE438 | Anti-Apobec1 Antibody

100 µg  
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      Replacement Information

      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, R WB, IH(P) Rb Affinity Purified Polyclonal Antibody
      Catalogue NumberABE438
      DescriptionAnti-Apobec1 Antibody
      Alternate Names
      • C->U-editing enzyme APOBEC-1
      • Apolipoprotein B mRNA-editing enzyme 1
      • HEPR
      Background InformationApolipoprotein B mRNA-editing enzyme 1 (Apobec1) is also known as C->U-editing enzyme APOBEC-1, and HEPR. Apobec1 is a member of the cytidine and deoxycytidylate deaminase family that is exclusively expressed in the small intestine. Apobec1 is a catalytic component of the apolipoprotein B mRNA editing enzyme complex which is responsible for postranscriptional mRNA editing. Apobec1 is also thought to be involved in the epigenetic regulation of gene expression by participating in DNA demethylation.
      Product Information
      FormatAffinity Purified
      • Human spleen tissue lysate
      PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      ApplicationDetect Apobec1 using this rabbit polyclonal antibody, Anti-Apobec1 Antibody validated for use in western blotting & IHC (Paraffin).
      Key Applications
      • Western Blotting
      • Immunohistochemistry (Paraffin)
      Application NotesImmunohistochemistry Analysis: A 1:500-2,000 dilution from a representative lot detected Apobec1 in rat small intestine and human colon tissue.
      Biological Information
      ImmunogenKLH-conjugated linear peptide corresponding to human Apobec1.
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      Species Reactivity
      • Human
      • Rat
      Species Reactivity NoteDemonstrated to react with Human and Rat. Other homologies: Mouse (79% sequence homology).
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • APOBEC1
      Purification MethodAffinity Purfied
      UniProt Number
      Molecular Weight~28 kDa observed
      Physicochemical Information
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in human spleen tissue lysate.

      Western Blotting Analysis: 0.1 µg/mL of this antibody detected Apobec1 in 10 µg of human spleen tissue lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information