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MAB8052 | Anti-Adenovirus Antibody, clone 20/11

MAB8052
100 µg  
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      Overview

      Replacement Information

      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H ELISA, FC, IF, IHC, IH(P) M Purified Monoclonal Antibody
      Description
      Catalogue NumberMAB8052
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionAnti-Adenovirus Antibody, clone 20/11
      Background InformationAdenoviruses are 65-80 nm, non-enveloped, regular icosahedron pathogens often associated with respiratory and gastrointestinal illness as well as conjunctivitis. Well over 40 types of adenoviruses have currently been recognized. In addition to their deleterious effects, adenoviruses have been used in vaccine production and in gene therapy. They also have the ability to trigger cell proliferation by interfering with host cellular anti-oncogenes. Since they are easy to prepare, multiple quickly and efficiently, and have the ability to infect and deliver their genome (including researcher-created constructs) to the nucleus of a variety of post-mitotic cells, adenoviruses are extremely valuable in research and medical applications ranging from virus/host cell interaction to the insertion of novel genes or regulatory mechanisms into eukaryotic cellular systems, to delivery of therapeutic anti-cancer genes.
      References
      Product Information
      FormatPurified
      Control
      • Adenovirus Control Slides, Catalogue Number 5009-5
      PresentationProtein A Purified mouse immunoglobulin in 20 mM sodium phosphate, 250 mM NaCl, pH. 7.6, with 0.1% sodium azide as a preservative.
      Applications
      ApplicationAnti-Adenovirus Antibody, clone 20/11 detects level of Adenovirus & has been published & validated for use in ELISA, FC, IF, IH, IH(P).
      Key Applications
      • ELISA
      • Flow Cytometry
      • Immunofluorescence
      • Immunohistochemistry
      • Immunohistochemistry (Paraffin)
      Application NotesEIA, IFA

      Immunohistochemistry: 1:200. In trypsinized (with 0.1% trypsin in Tris buffer pH 7.6 containing 0.1% Calcium Cloride; for 5-10 minutes at room temp.) paraffin embedded tissue. Do not use antigen retrieval.

      Flow cytometry.

      Final working dilutions and protocols must be determined by end user.
      Biological Information
      ImmunogenAdeno 3.
      Clone20/11
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostMouse
      SpecificityRecognizes All 41 serotypes of Adenovirus.
      IsotypeIgG1
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Purification MethodProtein A Purfied
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain at +2–8°C in convenient aliquots for up to 12 months. Do not store in a diluted format.

      During shipment, small volumes of product will occasionally become entrapped in the seal of the product vial. For products with volumes of 200μL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container's cap.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      SDS

      Title

      Safety Data Sheet (SDS) 

      Certificates of Analysis

      TitleLot Number
      MOUSE ANTI-ADENOVIRUS 2475763
      MOUSE ANTI-ADENOVIRUS MONOCLONAL ANTIBODY - 2388914 2388914
      MOUSE ANTI-ADENOVIRUS - 2533169 2533169
      MOUSE ANTI-ADENOVIRUS -2567311 2567311
      MOUSE ANTI-ADENOVIRUS -2605399 2605399
      MOUSE ANTI-ADENOVIRUS -2649195 2649195
      MOUSE ANTI-ADENOVIRUS -2673119 2673119
      MOUSE ANTI-ADENOVIRUS -2697596 2697596
      MOUSE ANTI-ADENOVIRUS -2727240 2727240
      MOUSE ANTI-ADENOVIRUS -2779498 2779498
      MOUSE ANTI-ADENOVIRUS -2822050 2822050
      MOUSE ANTI-ADENOVIRUS MONOCLONAL ANTIBODY - 2168251 2168251
      MOUSE ANTI-ADENOVIRUS MONOCLONAL ANTIBODY - 2196028 2196028
      MOUSE ANTI-ADENOVIRUS MONOCLONAL ANTIBODY - 2296726 2296726

      References | 26 Available | See All References

      Reference overviewPub Med ID
      Small RNA sequence analysis of adenovirus VA RNA-derived miRNAs reveals an unexpected serotype-specific difference in structure and abundance.
      Kamel, W; Segerman, B; Punga, T; Akusjärvi, G
      PloS one 9 e105746 2014

      Show Abstract
      25144466 25144466
      Tat-PTD-modified oncolytic adenovirus driven by the SCG3 promoter and ASH1 enhancer for neuroblastoma therapy.
      Jin, C; Yu, D; Čančer, M; Nilsson, B; Leja, J; Essand, M
      Human gene therapy 24 766-75 2013

      Show Abstract
      23889332 23889332
      The depuration dynamics of oysters (Crassostrea gigas) artificially contaminated with hepatitis A virus and human adenovirus.
      Adriana de Abreu Corrêa,Caroline Rigotto,Vanessa Moresco,Cristian Rafael Kleemann,Adriano Luiz Teixeira,Carlos Rogério Poli,Cláudia Maria Oliveira Simões,Célia Regina Monte Barardi
      Memórias do Instituto Oswaldo Cruz 107 2012

      Show Abstract
      22310530 22310530
      Coagulation factor IX mediates serotype-specific binding of species A adenoviruses to host cells.
      Lenman, A; Müller, S; Nygren, MI; Frängsmyr, L; Stehle, T; Arnberg, N
      Journal of virology 85 13420-31 2011

      Show Abstract
      21976659 21976659
      Detection and quantitation of infectious human adenoviruses and JC polyomaviruses in water by immunofluorescence assay.
      Calgua B, Barardi CR, Bofill-Mas S, Rodriguez-Manzano J, Girones R
      J Virol Methods 2010

      Show Abstract
      20863853 20863853
      Adenovirus delivery of human CD40 ligand gene confers direct therapeutic effects on carcinomas.
      L Vardouli,C Lindqvist,K Vlahou,A S I Loskog,A G Eliopoulos
      Cancer gene therapy 16 2009

      Show Abstract
      19461675 19461675
      Fiber mediated receptor masking in non-infected bystander cells restricts adenovirus cell killing effect but promotes adenovirus host co-existence.
      Rebetz J, Na M, Su C, Holmqvist B, Edqvist A, Nyberg C, Widegren B, Salford LG, Sjögren HO, Arnberg N, Qian Q, Fan X
      PLoS One 4 e8484. 2009

      Show Abstract Full Text Article
      20041185 20041185
      Biodistribution and kinetics of the novel selective oncolytic adenovirus M1 after systemic administration.
      Huang, X; Zhuang, L; Cao, Y; Gao, Q; Han, Z; Tang, D; Xing, H; Wang, W; Lu, Y; Xu, G; Wang, S; Zhou, J; Ma, D
      Molecular cancer therapeutics 7 1624-32 2008

      Show Abstract
      18566233 18566233
      Increased therapeutic efficacy of the prostate-specific oncolytic adenovirus Ad[I/PPT-E1A] by reduction of the insulator size and introduction of the full-length E3 region.
      Danielsson, A; Dzojic, H; Nilsson, B; Essand, M
      Cancer gene therapy 15 203-13 2008

      Show Abstract
      18188185 18188185
      Adenoviruses 16 and CV23 efficiently transduce human low-passage brain tumor and cancer stem cells.
      Skog, J; Edlund, K; Bergenheim, AT; Wadell, G
      Molecular therapy : the journal of the American Society of Gene Therapy 15 2140-5 2007

      Show Abstract
      17878898 17878898

      Data Sheet

      Title
      Anti-Adenovirus, clone 20/11 - Data Sheet