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MABC680 | Anti-AXL, clone 7E10 Antibody

100 µL  
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      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H WB, ICC M Ascites Monoclonal Antibody
      Catalogue NumberMABC680
      DescriptionAnti-AXL, clone 7E10 Antibody
      Alternate Names
      • Tyrosine-protein kinase receptor UFO
      • AXL
      Background InformationAXL receptor tyrosine kinase, also known as UFO, JTK11. AXL is a member of the receptor tyrosine kinase subfamily. Although it is similar to other receptor tyrosine kinases, this protein represents a unique structure of the extracellular region that juxtaposes IgL and FNIII repeats. AXL transduces signals from the extracellular matrix into the cytoplasm by binding growth factors like vitamin K-dependent protein growth-arrest-specific gene 6. AXL is involved in the stimulation of cell proliferation and can also mediate cell aggregation by homophilic binding. Alternatively spliced transcript variants encoding different isoforms have been identified.
      Product Information
      PresentationMouse monoclonal IgG1 ascitic fluid containing 0.03% sodium azide.
      ApplicationAnti-AXL, clone 7E10 is an antibody against AXL for use in Western Blotting and Immunocytochemistry.
      Key Applications
      • Western Blotting
      • Immunocytochemistry
      Application NotesImmunocytochemistry Analysis (ICC): A 1:200-1,000 dilution from a representative lot detected AXL in methanol-fixed HEK293 cells transfected with AXL-hIgGFc.

      Biological Information
      ImmunogenPurified recombinant extracellular fragment of human AXL fused with hIgGFc tag expressed in HEK293 cell line.
      ConcentrationPlease refer to lot specific datasheet.
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Gene Symbol
      • AXL
      • UFO
      Purification MethodUnpurified
      UniProt Number
      Molecular Weight~67 kDa observed. Uncharacterized bands may be observed in some lysate(s).
      Physicochemical Information
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in extracellular domain of human AXL.

      Western Blotting Analysis (WB): A 1:500-2,000 dilution of this antibody detected AXL in the extracellular domain.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at -20°C from date of receipt.
      Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
      Packaging Information
      Material Size100 µL
      Transport Information
      Supplemental Information

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      Life Science Research > Antibodies and Assays > Primary Antibodies