OP80 Anti-APC (Ab-7) Mouse mAb (CC-1)

OP80
Price could not be retrieved
Minimum Quantity needs to be mulitiple of
Upon Order Completion More Information
You Saved ()
 
Request Pricing
Limited AvailabilityLimited Availability
Stocked 
Discontinued
Limited Quantities Available
Available
    Remaining : Will advise
      Remaining : Will advise
      Will advise
      Contact Customer Service
      Contact Customer Service
      View Pricing & Availability

      Overview

      Replacement Information

      Key Specifications Table

      Species ReactivityHostAntibody Type
      H, M, R M Monoclonal Antibody

      Pricing & Availability

      Catalog Number AvailabilityPackaging Qty/Pack Price Quantity
      OP80-100UG
      Retrieving availability...
      Limited AvailabilityLimited Availability
      Stocked 
      Discontinued
      Limited Quantities Available
      Available
        Remaining : Will advise
          Remaining : Will advise
          Will advise
          Contact Customer Service
          Contact Customer Service

          Plastic ampoule 100 μg
          Retrieving price...
          Price could not be retrieved
          Minimum Quantity needs to be mulitiple of
          Upon Order Completion More Information
          You Saved ()
           
          Request Pricing
          Description
          OverviewRecognizes APC in oligodendrocytes and astrocytes.
        • Antibody Target Gene Symbol: APC
        • Target Synonym: AI047805, Apc7, AU020952, AW124434, BTPS2, DP2, DP2.5, DP3, Familial adenomatous polyposis, FAP, GS, Min, RATAPC
        • Entrez Gene Name: adenomatous polyposis coli
        • Hu Entrez ID: 324 (Related Antibodies: ST1150, OP62, OP47L, OP44)
        • Mu Entrez ID: 11789
        • Rat Entrez ID: 24205
        • Catalogue NumberOP80
          Brand Family Calbiochem®
          SynonymsAnti-Adenomatus Polyposis Coli
          References
          ReferencesBhat, R.V., et al. 1996. Glia 17, 169.
          Bhat, R.V., et al. 1994. Neuroscience Proceedings.
          Smith, K.J., et al. 1994. Cancer Res. 54, 3672.
          Smith, K.J., et al. 1993. Proc. Natl. Acad. Sci. USA 90, 2846.
          Su, L.-K., et al. 1993. Cancer Res. 53, 2728.
          Su, L.-K., et al. 1993. Science 262, 1734.
          Groden, J., et al. 1991. Cell 66, 589.
          Kinzler, K.W., et al. 1991. Science 251, 1366.
          Product Information
          FormLiquid
          FormulationIn 50 mM sodium phosphate buffer, 0.2% gelatin.
          Negative controlMOPC 21 cells
          Positive controlPurkinje cells or cerebellum tissue
          Preservative≤0.1% sodium azide
          Applications
          Application ReferencesImmunocytochemistry McTigue, D.M., et al. 2001. J. Neurosci. 21, 3392. Free Floating Sections Ding, H., et al. 2003. Cancer Res. 63, 1106.
          Key Applications Immunofluorescence
          Paraffin Sections
          Free-floating Sections
          Frozen Sections
          Immunocytochemistry
          Application NotesFrozen Sections (5 µg/ml)
          Immunofluorescence (5 µg/ml)
          Paraffin Sections (5 µg/ml, heat pre-treament required)
          Immunocytochemistry (see application references)
          Free Floating Sections (see application references)
          Application CommentsWell suited for IHC and IF studies of oligodendrocytes and optic nerves due to the antibody's staining of the cell body as opposed to the myelinated processes. Both frozen sections and formalin-fixed, paraffin-embedded brain sections can be used. Antibody should be titrated for optimal results in individual systems.
          Biological Information
          Immunogena recombinant protein consisting of amino acids 1-226 of APC
          CloneCC-1
          HostMouse
          IsotypeIgG2b
          Species Reactivity
          • Human
          • Mouse
          • Rat
          Antibody TypeMonoclonal Antibody
          Concentration Label Please refer to vial label for lot-specific concentration
          Physicochemical Information
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Blue Ice Only
          Toxicity Standard Handling
          Storage +2°C to +8°C
          Do not freeze Yes
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          Anti-APC (Ab-7) Mouse mAb (CC-1) SDS

          Title

          Safety Data Sheet (SDS) 

          Anti-APC (Ab-7) Mouse mAb (CC-1) Certificates of Analysis

          TitleLot Number
          OP80

          References

          Reference overview
          Bhat, R.V., et al. 1996. Glia 17, 169.
          Bhat, R.V., et al. 1994. Neuroscience Proceedings.
          Smith, K.J., et al. 1994. Cancer Res. 54, 3672.
          Smith, K.J., et al. 1993. Proc. Natl. Acad. Sci. USA 90, 2846.
          Su, L.-K., et al. 1993. Cancer Res. 53, 2728.
          Su, L.-K., et al. 1993. Science 262, 1734.
          Groden, J., et al. 1991. Cell 66, 589.
          Kinzler, K.W., et al. 1991. Science 251, 1366.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision16-November-2007 JSW
          SynonymsAnti-Adenomatus Polyposis Coli
          ApplicationFrozen Sections (5 µg/ml)
          Immunofluorescence (5 µg/ml)
          Paraffin Sections (5 µg/ml, heat pre-treament required)
          Immunocytochemistry (see application references)
          Free Floating Sections (see application references)
          DescriptionPurified mouse monoclonal antibody generated by immunizing CB6 F1 mice with the specified immunogen and fusing splonocytes with SP2/O mouse myeloma cells. Recognizes the ~312 kDa APC protein.
          BackgroundGerm line mutations in the APC gene are responsible for familial adenomatous polyposis and somatic mutations contribute to sporadic colorectal cancer. The 312 kDa APC protein is expressed in all tissues and localized to the cytoskeletal architecture in an insoluble complex with β-catenin. The APC (Ab-7) mouse monoclonal antibody clone CC-1 decorates oligodendrocyte cell bodies, purkinje cells, astrocytes, and optic nerve cell bodies of formalin-fixed, paraffin-embedded, or fresh frozen sections from human, mouse, and rat brain. Dectection of APC (Ab-7) can be perfomed using immunofluorescence or immunohistochemistry techniques.
          HostMouse
          Immunogena recombinant protein consisting of amino acids 1-226 of APC
          CloneCC-1
          IsotypeIgG2b
          Specieshuman, mouse, rat
          Positive controlPurkinje cells or cerebellum tissue
          Negative controlMOPC 21 cells
          FormLiquid
          FormulationIn 50 mM sodium phosphate buffer, 0.2% gelatin.
          Concentration Label Please refer to vial label for lot-specific concentration
          Preservative≤0.1% sodium azide
          CommentsWell suited for IHC and IF studies of oligodendrocytes and optic nerves due to the antibody's staining of the cell body as opposed to the myelinated processes. Both frozen sections and formalin-fixed, paraffin-embedded brain sections can be used. Antibody should be titrated for optimal results in individual systems.
          Storage +2°C to +8°C
          Do Not Freeze Yes
          Toxicity Standard Handling
          ReferencesBhat, R.V., et al. 1996. Glia 17, 169.
          Bhat, R.V., et al. 1994. Neuroscience Proceedings.
          Smith, K.J., et al. 1994. Cancer Res. 54, 3672.
          Smith, K.J., et al. 1993. Proc. Natl. Acad. Sci. USA 90, 2846.
          Su, L.-K., et al. 1993. Cancer Res. 53, 2728.
          Su, L.-K., et al. 1993. Science 262, 1734.
          Groden, J., et al. 1991. Cell 66, 589.
          Kinzler, K.W., et al. 1991. Science 251, 1366.
          Application referencesImmunocytochemistry McTigue, D.M., et al. 2001. J. Neurosci. 21, 3392. Free Floating Sections Ding, H., et al. 2003. Cancer Res. 63, 1106.